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Brachystemma

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Brachystemma calycinum
Scientific classification
Kingdom:
(unranked):
(unranked):
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Order:
Family:
Genus:
Brachystemma

Species:
B. calycinum
Binomial name
Brachystemma calycinum

Brachystemma calycinum is an indigenous plant of southwestern China and has shown promise as a natural adjunct anti-inflammatory agent for treatment of osteoarthritis in humans and dogs.[1][unreliable source?] This plant reported has active ingredients which result in decreased levels of protease activated receptor 2 (PAR 2), inducible nitric oxide synthase, and matrix metalloprotease 13.[2]

References

  1. ^ Maxim Moreau; Bertrand Lussier; Jean-Pierre Pelletier; Johanne Martel-Pelletier; Christian Bédard; Dominique Gauvin; Eric Troncy (2012). "Brachystemma calycinum D. Don effectively reduces the locomotor disability in dogs with naturally occurring osteoarthritis: a randomized placebo-controlled trial". Evidence-based Complementary and Alternative Medicine. 2012: 646191. doi:10.1155/2012/646191. PMC 3403515. PMID 22844335.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  2. ^ Christelle Boileau; Johanne Martel-Pelletier; Judith Caron; Frédéric Paré; Eric Troncy; Maxim Moreau; Jean-Pierre Pelletier (2010). "Oral treatment with a Brachystemma calycinum D. Don plant extract reduces disease symptoms and the development of cartilage lesions in experimental dog osteoarthritis: inhibition of protease-activated receptor 2". Annals of the Rheumatic Diseases. 69 (6): 1179–1184. doi:10.1136/ard.2009.110965.