Brian Hooker (bioengineer)

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search

Brian S. Hooker is a biologist and chemist at Simpson University. He is known for claiming that vaccines cause autism.


In 1985, Hooker earned his bachelor of science degree in chemical engineering, from California State Polytechnic University, Pomona, California. He earned his master's of science degree in 1988 and his doctorate in 1990, both in chemical engineering, from Washington State University, in Pullman, Washington.[citation needed]


Hooker formerly managed applied plant and fungal molecular biology research projects, including development of plant-based biosensors and transgenic production systems for human pharmaceutical proteins and industrial enzymes at the Pacific Northwest National Laboratory, where systems biology researchers are focused on understanding gene and protein networks involved in individual cell signaling, communication between cells in communities, and cellular metabolic pathways. Hooker has also been involved in research on microbial kinetics and transport mathematical modeling, design, development, and support for biological destruction of chlorinated organic hydrocarbons, development of tP4 transgenic plant protein production platform technology, and development of the RT3D bioremediation/natural attenuation software package.[citation needed]

He left PNNL in 2009, and was hired as an associate professor at Simpson University where he specializes in biology and chemistry. Simpson University is a private Christian University of liberal arts and professional studies offering undergraduate, graduate and teaching credential programs.

Hooker is known for his anti-vaccine activism and his claims of conflicts of interest within the Centers for Disease Control and Prevention. He is a board member at Focus Autism,[1] an organization which believes in the "ongoing cover-up of the vaccine/autism link".[2]

Hooker and Andrew Wakefield have alleged scientific fraud, conspiracy, and coverup on the part of the Centers for Disease Control and Prevention with regard to the supposed link between vaccines and autism.[3][4] An online video describing this situation was debunked by Snopes.[5]

Recognition and controversy[edit]

In 2014, Hooker's paper titled "Measles-mumps-rubella vaccination timing and autism among young African American boys: a reanalysis of CDC data" was retracted from the journal Translational Neurodegeneration.[6] According to Hooker, the journal falsely accused him of a conflict of interest: Hooker has been involved in vaccine/biologic litigation[7] and provided no scientific rationale for the retraction.[8]

Personal life[edit]

Hooker has publicly said that his son was "permanently damaged" by vaccines.[3]

Selected publications[edit]

  • Dai Z, BS Hooker, RD Quesenberry, and J Gao. “Expression of Trichoderma reesei exo-cellobiohydrolase I (CBH I) in transgenic tobacco leaves and calli”, Applied Biochemistry and Biotechnology, 1999, 77-79(9):689-699
  • Dai Z, BS Hooker, DB Anderson, and SR Thomas.“Improved plant-based production of E1 endoglucanase using potato:expression optimization and tissue targeting”, Molecular Breeding, 2000, 6(3):277-285.
  • Gao J, BS Hooker, and DB Anderson. 2004. “Expression of Functional Human Coagulation Factor XIII A-domain in Plant Cell Suspensions and Whole Plants.” Protein Expression and Purification 37(1):89-96.
  • Hooker, Brian S., Hettich, Robert L., Hurst, Gregory B., Kennel, Stephen J., Lankford, Patricia K., Chiann-Tso Lin, Lye Meng Markillie, Mayer-Clumbridge, M. Uljana, Pelletier, Dale A., Liang, Shi, Squier, Thomas C., Strader, Michael B., VerBerkmoes, Nathan C., "Isolation and Characterization of Protein Complexes from Shewanella oneidensis and Rhodopseudomonas palustris", Genomics: GTL Contractor—Grantee Workshop II, Washington, DC, February 29-March 2, 2004
  • Trelka, Jeffrey A., Hooker, Brian S. "Specific Carbohydrate Dietary Trial: Understanding the Effectiveness of a Specific Carbohydrate Dietary Intervention In Autistic Children", 2004
  • Markillie LM, CT Lin, JN Adkins, DL Auberry, EA Hill, BS Hooker, PA Moore, RJ Moore, L Shi, HS Wiley, and V Kery, “A simple protein complex purification and identification method for high throughput mapping of protein interaction networks”, Journal of Proteome Research, 2005
  • Liang Shi, Jiann-Trzwo Lin, Lye M. Markillie, Thomas C. Squier, and Brian S. Hooker, “Overexpression of multi-heme C-type cytochromes” - Expression of recombinant decaheme cytochrome MtrA in Shewanella oneidensis MR-1 by a directional TOPO cloning-based system. BioTechniques, 2005, 38(2):297-9.


  1. ^ Lupkin, Sydney (October 9, 2014). "How a Now-Retracted Autism Study Went Viral -- Again". ABC News. Retrieved April 14, 2019.
  2. ^ Lupkin, Sydney (October 9, 2014). "How a Now-Retracted Autism Study Went Viral -- Again". ABC News. Retrieved April 14, 2019.
  3. ^ a b "Did a high ranking whistleblower really reveal that the CDC covered up proof that vaccines cause autism in African-American boys?". Retrieved 16 April 2019.
  4. ^ WesselApr. 27, Lindzi (25 April 2017). "Four vaccine myths and where they came from". Science | AAAS. Retrieved 16 April 2019.
  5. ^ "FACT CHECK: Fraud at the CDC Uncovered?". Retrieved 16 April 2019.
  6. ^ Retraction Note: Measles-mumps-rubella vaccination timing and autism among young African American boys: a reanalysis of CDC data | Translational Neurodegeneration | Full Text
  7. ^ Hooker, Brian S. (2014). "Measles-mumps-rubella vaccination timing and autism among young african american boys: A reanalysis of CDC data". Translational Neurodegeneration. 3: 22. doi:10.1186/2047-9158-3-16. PMC 4183946. PMID 25285211.
  8. ^ CDC Data Manipulation Exposed: Four Years Later | Journal of American Physicians and Surgeons | Full Text