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Brigitta Stockinger

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Gitta Stockinger
Born
Brigitta Stockinger
Alma materUniversity of Mainz (PhD)
Awards
Scientific career
Fields
Institutions
Websitenimr.mrc.ac.uk/research/gitta-stockinger

Brigitta Stockinger, FMedSci, FRS, is a molecular immunologist in the Francis Crick Institute London. Stockinger's research has contributed insights into the regulation and maintenance of peripheral T cell immune responses.[1][2][3][4][5][6][7][8][9][10]

Education

Stockinger was educated at the University of Mainz where she was awarded a PhD in Biology.

Career

  • 1985–1991 - Basel Institute for Immunology (Member)
  • 1991-2015 - Division of Molecular Immunology, MRC National Institute for Medical Research (Head)
  • 2015–present- Principal Investigator in the Francis Crick Institute

Awards and honours

Stockinger was elected a Fellow of the Royal Society in 2013, her nomination reads:

Brigitta Stockinger has contributed insights regulation and maintenance of peripheral T cell immune responses. She was the first to define mechanisms underlying the differentiation of Th17 cells and demonstrated substantial pasticity in TH17 cell function depending on the inflammatory environment. Stockinger identified the Aryl hydrocarbon receptor (AhR) as connector between the immune system and environmental stimuli, showing that it shapes the functional differentiation of Th17 effector cells. The AhR links their role in host defence as well as their role in autoimmunity to environmental factors. Research into the physiological roles of AhR in the immune system beyond its role in toxicology provides a major breakthrough for both disciplines.[11]

In 2008, she was elected a member of European Molecular Biology Organization (EMBO).

References

  1. ^ Veldhoen, M.; Hirota, K.; Westendorf, A. M.; Buer, J.; Dumoutier, L.; Renauld, J. C.; Stockinger, B. (2008). "The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins". Nature. 453 (7191): 106–109. doi:10.1038/nature06881. PMID 18362914.
  2. ^ Veldhoen, M.; Uyttenhove, C.; Van Snick, J.; Helmby, H.; Westendorf, A.; Buer, J.; Martin, B.; Wilhelm, C.; Stockinger, B. (2008). "Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset". Nature Immunology. 9 (12): 1341–1346. doi:10.1038/ni.1659.
  3. ^ Veldhoen, M; Hocking, R. J.; Atkins, C. J.; Locksley, R. M.; Stockinger, B (2006). "TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells". Immunity. 24 (2): 179–89. doi:10.1016/j.immuni.2006.01.001. PMID 16473830.
  4. ^ Stockinger, B. (2013). "Open questions: A few that need answers in immunology". BMC Biology. 11: 115. doi:10.1186/1741-7007-11-115.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  5. ^ Brigitta Stockinger publications indexed by Microsoft Academic
  6. ^ Brigitta Stockinger's publications indexed by the Scopus bibliographic database. (subscription required)
  7. ^ Vieira, P. L.; Christensen, J. R.; Minaee, S; O'Neill, E. J.; Barrat, F. J.; Boonstra, A; Barthlott, T; Stockinger, B; Wraith, D. C.; O'Garra, A (2004). "IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells". Journal of Immunology. 172 (10): 5986–93. doi:10.4049/jimmunol.172.10.5986. PMID 15128781.
  8. ^ Stockinger, B.; Veldhoen, M. (2007). "Differentiation and function of Th17 T cells". Current Opinion in Immunology. 19 (3): 281–6. doi:10.1016/j.coi.2007.04.005. PMID 17433650.
  9. ^ Buckley, C. D.; Gilroy, D. W.; Serhan, C. N.; Stockinger, B.; Tak, P. P. (2012). "The resolution of inflammation". Nature Reviews Immunology. 13: 59–66. doi:10.1038/nri3362.
  10. ^ Stockinger, B; Zal, T; Zal, A; Gray, D (1996). "B cells solicit their own help from T cells". The Journal of Experimental Medicine. 183 (3): 891–9. doi:10.1084/jem.183.3.891. PMC 2192359. PMID 8642293.
  11. ^ http://royalsociety.org/people/brigitta-stockinger/


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