C1QTNF3

C1QTNF3
Identifiers
Aliases	C1QTNF3, C1ATNF3, CORCS, CORS, CORS-26, CORS26, CTRP3, C1q and tumor necrosis factor related protein 3, C1q and TNF related 3
External IDs	OMIM: 612045; MGI: 1932136; HomoloGene: 12788; GeneCards: C1QTNF3; OMA:C1QTNF3 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	34,043,213 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	10,980,236 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; Achilles tendon; ; cartilage tissue; ; vena cava; ; cardia; ; right testis; ; left testis; ; skin of hip; ; synovial joint; ; epithelium of colon;
	Top expressed in
	right kidney; ; dermis; ; human fetus; ; muscle of thorax; ; proximal tubule; ; body of femur; ; human kidney; ; cervix; ; condyle; ; umbilical cord;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; molecular function;
Cellular component	extracellular region; collagen; extracellular exosome; membrane; extracellular space;
Biological process	cellular triglyceride homeostasis; negative regulation of monocyte chemotactic protein-1 production; negative regulation of gluconeogenesis; protein trimerization; fat cell differentiation; negative regulation of inflammatory response; negative regulation of gene expression; positive regulation of adiponectin secretion; negative regulation of NIK/NF-kappaB signaling;
	Sources:Amigo / QuickGO
Orthologs
	114899
	81799
	ENSG00000082196
	ENSMUSG00000058914
	Q9BXJ4
	Q9ES30
	NM_181435; NM_030945
	NM_001204134; NM_030888
	NP_112207; NP_852100
	NP_001191063; NP_112150
	Wikidata
View/Edit Human	View/Edit Mouse

Complement C1q tumor necrosis factor-related protein 3 is a protein that in humans is encoded by the C1QTNF3 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000082196 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000058914 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wölfing B, Buechler C, Weigert J, Neumeier M, Aslanidis C, Schöelmerich J, Schäffler A (Jul 2008). "Effects of the new C1q/TNF-related protein (CTRP-3) "cartonectin" on the adipocytic secretion of adipokines". Obesity. 16 (7): 1481–1486. doi:10.1038/oby.2008.206. PMID 18421280. S2CID 40979522.
^ "Entrez Gene: C1QTNF3 C1q and tumor necrosis factor related protein 3".

External links

Human C1QTNF3 genome location and C1QTNF3 gene details page in the UCSC Genome Browser.

Akiyama H, Furukawa S, Wakisaka S, Maeda T (Oct 2007). "CTRP3/cartducin promotes proliferation and migration of endothelial cells". Molecular and Cellular Biochemistry. 304 (1–2): 243–248. doi:10.1007/s11010-007-9506-6. PMID 17534697. S2CID 25647563.
Wurm S, Neumeier M, Weigert J, Schäffler A, Buechler C (2007). "Plasma levels of leptin, omentin, collagenous repeat-containing sequence of 26-kDa protein (CORS-26) and adiponectin before and after oral glucose uptake in slim adults". Cardiovascular Diabetology. 6: 7. doi:10.1186/1475-2840-6-7. PMC 1804262. PMID 17311679.
Otsuki T, Ota T, Nishikawa T, Hayashi K, Suzuki Y, Yamamoto J, Wakamatsu A, Kimura K, Sakamoto K, Hatano N, Kawai Y, Ishii S, Saito K, Kojima S, Sugiyama T, Ono T, Okano K, Yoshikawa Y, Aotsuka S, Sasaki N, Hattori A, Okumura K, Nagai K, Sugano S, Isogai T (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Research. 12 (2): 117–126. doi:10.1093/dnares/12.2.117. PMID 16303743.
Schäffler A, Ehling A, Neumann E, Herfarth H, Paul G, Tarner I, Gay S, Schölmerich J, Müller-Ladner U (Nov 2003). "Genomic organization, promoter, amino acid sequence, chromosomal localization, and expression of the human gene for CORS-26 (collagenous repeat-containing sequence of 26-kDa protein)". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1630 (2–3): 123–9. doi:10.1016/j.bbaexp.2003.08.013. PMID 14654242.
Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A (Oct 2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Research. 13 (10): 2265–2270. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Maeda T, Abe M, Kurisu K, Jikko A, Furukawa S (Feb 2001). "Molecular cloning and characterization of a novel gene, CORS26, encoding a putative secretory protein and its possible involvement in skeletal development". The Journal of Biological Chemistry. 276 (5): 3628–3634. doi:10.1074/jbc.M007898200. PMID 11071891.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000082196 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000058914 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid18421280-5] Wölfing B, Buechler C, Weigert J, Neumeier M, Aslanidis C, Schöelmerich J, Schäffler A (Jul 2008). "Effects of the new C1q/TNF-related protein (CTRP-3) "cartonectin" on the adipocytic secretion of adipokines". Obesity. 16 (7): 1481–1486. doi:10.1038/oby.2008.206. PMID 18421280. S2CID 40979522.

[entrez-6] "Entrez Gene: C1QTNF3 C1q and tumor necrosis factor related protein 3".

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References

External links

Further reading