CENTG3

AGAP3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3IHW
Identifiers
Aliases	AGAP3, AGAP-3, CENTG3, CRAG, MRIP-1, cnt-g3, ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
External IDs	OMIM: 616813; MGI: 2183446; HomoloGene: 23742; GeneCards: AGAP3; OMA:AGAP3 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	151,144,436 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	24,707,045 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; right frontal lobe; ; Brodmann area 9; ; cingulate gyrus; ; anterior cingulate cortex; ; prefrontal cortex; ; amygdala; ; hypothalamus; ; nucleus accumbens; ; anterior pituitary;
	Top expressed in
	superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; primary visual cortex; ; neural layer of retina; ; ventricular zone; ; lip; ; muscle of thigh; ; cerebellar cortex; ; otic vesicle; ; saccule;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; GTP binding; metal ion binding; GTPase activator activity; GTPase activity; polyubiquitin modification-dependent protein binding;
Cellular component	membrane; nucleus; cytoplasm; cell periphery;
Biological process	positive regulation of GTPase activity; signal transduction; cellular response to reactive oxygen species; proteasome-mediated ubiquitin-dependent protein catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	116988
	213990
	ENSG00000133612
	ENSMUSG00000023353
	Q96P47; Q86ST5
	Q8VHH5
NM_001042535; NM_001281300; NM_001308304; NM_001308305; NM_031946;
	NM_001350102; NM_001350103; NM_001350104
	NM_001256431; NM_139153; NM_001359881
NP_001036000; NP_001268229; NP_001295233; NP_001295234; NP_114152;
	NP_001337031; NP_001337032; NP_001337033; NP_001036000.1; NP_001295233.1; NP_001295234.1
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 is an enzyme that in humans is encoded by the AGAP3 gene.^[5]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000133612 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000023353 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: CENTG3 centaurin, gamma 3".

References

Further reading