CNDP1

CNDP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3DLJ
Identifiers
Aliases	CNDP1, CN1, CPGL2, HsT2308, carnosine dipeptidase 1 (metallopeptidase M20 family), carnosine dipeptidase 1
External IDs	OMIM: 609064; MGI: 2451097; HomoloGene: 57178; GeneCards: CNDP1; OMA:CNDP1 - orthologs
Gene location (Human)
Chr.	Chromosome 18 (human)
End	74,587,212 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	84,668,220 bp
RNA expression pattern
	Top expressed in
	inferior ganglion of vagus nerve; ; endothelial cell; ; medulla oblongata; ; corpus callosum; ; pons; ; superior vestibular nucleus; ; ventral tegmental area; ; subthalamic nucleus; ; substantia nigra; ; globus pallidus;
	Top expressed in
	proximal tubule; ; kidney; ; secondary oocyte; ; jejunum; ; renal pelvis; ; renal calyx; ; sciatic nerve; ; uterus; ; ileum; ; parotid gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	carboxypeptidase activity; hydrolase activity; peptidase activity; metallopeptidase activity; metal ion binding; dipeptidase activity;
Cellular component	extracellular region; cytosol;
Biological process	metabolism; proteolysis; regulation of cellular protein metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	84735
	338403
	ENSG00000150656
	ENSMUSG00000056162
	Q96KN2
	Q8BUG2
	NM_032649
	NM_177450
	NP_116038
	NP_803233
	Wikidata
View/Edit Human	View/Edit Mouse

Beta-Ala-His dipeptidase is an enzyme that in humans is encoded by the CNDP1 gene.^[5]^[6]

The metabolic disorder Carnosinemia may be caused by mutations in this gene.

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000150656 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000056162 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Teufel M, Saudek V, Ledig JP, Bernhardt A, Boularand S, Carreau A, Cairns NJ, Carter C, Cowley DJ, Duverger D, Ganzhorn AJ, Guenet C, Heintzelmann B, Laucher V, Sauvage C, Smirnova T (Feb 2003). "Sequence identification and characterization of human carnosinase and a closely related non-specific dipeptidase". J Biol Chem. 278 (8): 6521–31. doi:10.1074/jbc.M209764200. PMID 12473676.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family)".