This is an old revision of this page, as edited by Julialturner(talk | contribs) at 21:20, 17 May 2016(updating infobox to use wikidata as source). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.
Revision as of 21:20, 17 May 2016 by Julialturner(talk | contribs)(updating infobox to use wikidata as source)
Cytochrome c oxidase subunit 8A is a protein that in humans is encoded by the COX8Agene.[5] Cytochrome c oxidase 8A is a subunit of the cytochrome c oxidase complex, also known as Complex IV.
Structure
COX8A is a 7.6 kDa protein composed of 69 amino acids.[6][7] This gene encodes the nuclear-encoded subunit 8A of the human mitochondrialrespiratory chain enzyme complex cytochrome c oxidase. The complex consists of 13 mitochondrial- and nuclear-encoded subunits.[5]
Function
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrialrespiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex.[5]
