Jump to content

CST1

From Wikipedia, the free encyclopedia
(Redirected from CST1 (gene))
CST1
Identifiers
AliasesCST1, cystatin SN
External IDsOMIM: 123855; HomoloGene: 88653; GeneCards: CST1; OMA:CST1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001898

n/a

RefSeq (protein)

NP_001889

n/a

Location (UCSC)Chr 20: 23.75 – 23.75 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Cystatin-SN is a protein that in humans is encoded by the CST1 gene.[3]

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a cysteine proteinase inhibitor found in saliva, tears, urine, and seminal fluid.[3]

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000170373Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ a b "Entrez Gene: CST1 cystatin SN".
[edit]

Further reading

[edit]