CST7 (gene)

CST7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2CH9
Identifiers
Aliases	CST7, CMAP, cystatin F
External IDs	OMIM: 603253; MGI: 1298217; HomoloGene: 37832; GeneCards: CST7; OMA:CST7 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	24,959,928 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	150,420,864 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; blood; ; bone marrow; ; bone marrow cells; ; trabecular bone; ; spleen; ; right lung; ; gonad; ; upper lobe of left lung; ; lymph node;
	Top expressed in
	mesenteric lymph nodes; ; granulocyte; ; morula; ; tibiofemoral joint; ; bone marrow; ; blood; ; spleen; ; fetal liver hematopoietic progenitor cell; ; thymus; ; decidua;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	peptidase inhibitor activity; endopeptidase inhibitor activity; protein binding; protease binding; cysteine-type endopeptidase inhibitor activity; protein homodimerization activity;
Cellular component	cytoplasm; extracellular region; extracellular space; lysosome; endosome; late endosome; multivesicular body; endoplasmic reticulum; Golgi apparatus; cytoplasmic vesicle;
Biological process	negative regulation of peptidase activity; immune response; negative regulation of cysteine-type endopeptidase activity; negative regulation of endopeptidase activity; positive regulation of myelination; inhibition of cysteine-type endopeptidase activity; negative regulation of microglial cell activation;
	Sources:Amigo / QuickGO
Orthologs
	8530
	13011
	ENSG00000077984
	ENSMUSG00000068129
	O76096
	O89098
	NM_003650
	NM_009977
	NP_003641
	NP_034107
	Wikidata
View/Edit Human	View/Edit Mouse

Cystatin-F is a protein that in humans is encoded by the CST7 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000077984 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000068129 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ni J, Fernandez MA, Danielsson L, Chillakuru RA, Zhang J, Grubb A, Su J, Gentz R, Abrahamson M (Oct 1998). "Cystatin F is a glycosylated human low molecular weight cysteine proteinase inhibitor". J Biol Chem. 273 (38): 24797–804. doi:10.1074/jbc.273.38.24797. PMID 9733783.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ Halfon S, Ford J, Foster J, Dowling L, Lucian L, Sterling M, Xu Y, Weiss M, Ikeda M, Liggett D, Helms A, Caux C, Lebecque S, Hannum C, Menon S, McClanahan T, Gorman D, Zurawski G (Aug 1998). "Leukocystatin, a new Class II cystatin expressed selectively by hematopoietic cells". J Biol Chem. 273 (26): 16400–8. doi:10.1074/jbc.273.26.16400. PMID 9632704.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: CST7 cystatin F (leukocystatin)".

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External links

The MEROPS online database for peptidases and their inhibitors: I25.007
Human CST7 genome location and CST7 gene details page in the UCSC Genome Browser.

References

External links

Further reading