CXXC5

CXXC5
Identifiers
Aliases	CXXC5, CF5, RINF, WID, HSPC195, CXXC finger protein 5
External IDs	OMIM: 612752; MGI: 1914643; HomoloGene: 9517; GeneCards: CXXC5; OMA:CXXC5 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	139,683,882 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	35,994,741 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; renal medulla; ; inferior ganglion of vagus nerve; ; medulla oblongata; ; ventral tegmental area; ; superior vestibular nucleus; ; cerebellum; ; nasal epithelium; ; pons; ; cerebellar hemisphere;
	Top expressed in
	Epithelium of choroid plexus; ; tail of embryo; ; lens; ; ciliary body; ; iris; ; cerebellar cortex; ; epithelium of lens; ; islet of Langerhans; ; Rostral migratory stream; ; vestibular membrane of cochlear duct;
	More reference expression data
	n/a
Gene ontology
Molecular function	sequence-specific DNA binding; DNA binding; zinc ion binding; transcription factor binding; protein binding; signal transducer activity; metal ion binding;
Cellular component	nucleus; nucleoplasm; cytoplasm; cytosol;
Biological process	positive regulation of I-kappaB kinase/NF-kappaB signaling; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	51523
	67393
	ENSG00000171604
	ENSMUSG00000046668
	Q7LFL8
	Q91WA4
NM_016463; NM_001317199; NM_001317200; NM_001317201; NM_001317202;
	NM_001317203; NM_001317204; NM_001317205; NM_001317206; NM_001317207; NM_001317208; NM_001317209; NM_001317210; NM_001317211
	NM_133687; NM_001357458; NM_001357459
NP_001304128; NP_001304129; NP_001304130; NP_001304131; NP_001304132;
	NP_001304133; NP_001304134; NP_001304135; NP_001304136; NP_001304137; NP_001304138; NP_001304139; NP_001304140; NP_057547
	NP_598448; NP_001344387; NP_001344388
	Wikidata
View/Edit Human	View/Edit Mouse

CXXC-type zinc finger protein 5 is a protein that in humans is encoded by the CXXC5 gene.^[5]^[6]^[7]^[8]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000171604 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000046668 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Nov 2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
^ Andersson T, Sodersten E, Duckworth JK, Cascante A, Fritz N, Sacchetti P, Cervenka I, Bryja V, Hermanson O (Feb 2009). "CXXC5 is a novel BMP4-regulated modulator of Wnt signaling in neural stem cells". J Biol Chem. 284 (6): 3672–81. doi:10.1074/jbc.M808119200. PMID 19001364.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ Pendino F, Nguyen E, Jonassen I, Dysvik B, Azouz A, Lanotte M, Segal-Bendirdjian E, Lillehaug JR (Apr 2009). "Functional involvement of RINF, retinoid-inducible nuclear factor (CXXC5), in normal and tumoral human myelopoiesis". Blood. 113 (14): 3172–81. doi:10.1182/blood-2008-07-170035. PMID 19182210.
^ "Entrez Gene: CXXC5 CXXC finger 5".

External links

Human CXXC5 genome location and CXXC5 gene details page in the UCSC Genome Browser.

References

External links

Further reading