Casbene synthase
Appearance
casbene synthase | |||||||||
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Identifiers | |||||||||
EC no. | 4.2.3.8 | ||||||||
CAS no. | 69106-45-2 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a casbene synthase (EC 4.2.3.8) is an enzyme that catalyzes the chemical reaction
- geranylgeranyl diphosphate casbene + diphosphate
Hence, this enzyme has one substrate, geranylgeranyl diphosphate, and two products, casbene and diphosphate.
This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, casbene-forming). Other names in common use include casbene synthetase, and geranylgeranyl-diphosphate diphosphate-lyase (cyclizing). This enzyme participates in diterpenoid biosynthesis.
References
- Moesta P, West CA (1985). "Casbene synthetase: regulation of phytoalexin biosynthesis in Ricinus communis L. seedlings. Purification of casbene synthetase and regulation of its biosynthesis during elicitation". Arch. Biochem. Biophys. 238 (1): 325–33. doi:10.1016/0003-9861(85)90171-7. PMID 3985625.