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Citrate dehydratase

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citrate dehydratase
Identifiers
EC no.4.2.1.4
CAS no.9024-39-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a citrate dehydratase (EC 4.2.1.4) is an enzyme that catalyzes the chemical reaction

citrate cis-aconitate + H2O

Hence, this enzyme has one substrate, citrate, and two products, cis-aconitate and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is citrate hydro-lyase (cis-aconitate-forming). This enzyme is also called citrate hydro-lyase.

References

  • NEILSON NE (1955). "The aconitase of Aspergillus niger". Biochim. Biophys. Acta. 17 (1): 139–40. doi:10.1016/0006-3002(55)90330-9. PMID 13239639.