The Clays were an influential nineteenth-century U.S. political and business dynasty.
List of Clays
- Brutus Junius Clay (1808–1878), U.S. Congressman from Kentucky.
- Brutus J. Clay II (1847-1932), minister to Switzerland, son of Cassius Marcellus Clay
- Cassius Marcellus Clay (politician) (1810–1903), publisher, U.S. general, U.S. minister to Russia.
- Clement Claiborne Clay (1816–1882), U.S. Senator from Alabama.
- Clement Comer Clay (1789–1866), U.S. Senator from Alabama.
- Green Clay (1757–1828), member of the Virginia and Kentucky legislatures; Speaker of the Kentucky Senate.
- Green Clay Smith (1826–1895), U.S. Congressman from Kentucky and Territorial Governor of Montana.
- Henry Clay (1777–1852), U.S. Representative and Senator from Kentucky; Speaker of the House of Representatives; U.S. Secretary of State.
- Henry Clay, Jr. (1811–1847), Lt. Col. in the Second Kentucky Regiment, killed in the Battle of Buena Vista.
- Henry "Harry" Clay (1849–1884), Arctic explorer; candidate for Kentucky House of Representatives.
- James Brown Clay (1817–1864), U.S. Chargé d'affaires at Lisbon, Portugal; U.S. Representative from Kentucky; member of the Peace Conference of 1861; commissioned to raise a regiment for the Confederate States of America.
- James Brown Clay (1848–1906), aide-de-camp to Major General John C. Breckinridge.
- John Morrison Clay (1821–1887), thoroughbred racer and breeder.
- Josephine Russell Clay (1835–1920), thoroughbred breeder and author.
- Laura Clay (1849–1941), a leader in the women's suffrage movement.
- Mary Barr Clay (1839–1924), president of the American Woman Suffrage Association.
- Matthew Clay (1754–1815), U.S. Representative from Virginia.
- Matthew Clay (c.1795-1827), member of the Alabama Senate.
- Nathaniel W. Watkins (1796-1876), Confederate Army brigadier general and Speaker of the Missouri House of Representatives.
- Nestor Clay (1799–1835), Texas pioneer; representative at the 1832 and 1833 Texas Conventions.
- Susan Clay Sawitzky (1897–1981), U.S. poet.
- Tacitus Thomas Clay (1824–1868), mayor of Independence, Texas; Confederate army officer.
- Thomas Clay (b 1750), member of the first Kentucky Constitutional Convention.
- Thomas C. McCreery (1816–1890), U.S. Senator from Kentucky.
- Thomas Hart Clay (1803–1871), U.S. minister to Nicaragua and Honduras.
- Thomas Jacob Clay (1853–1939) Second Lieutenant, U.S. Army, who participated in the second capture of Geronimo.
- William Claude Clay (1917–2004) member of 2677th Office of Strategic Services Regiment (United States) and 2671st Special Reconnaissance Battalion (United States) of the Office of Strategic Services, won various medals of valor.