Omphalotus subilludens

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Omphalotus subilludens
Scientific classification
Kingdom: Fungi
Division: Basidiomycota
Class: Agaricomycetes
Order: Agaricales
Family: Marasmiaceae
Genus: Omphalotus
Species: O. subilludens
Binomial name
Omphalotus subilludens
(Murrill) H.E. Bigelow 1982
Synonyms

Clitocybe subilludens (Murrill) Murrill 1945[1]
Monodelphus subilludens Murrill 1945

Omphalotus subilludens is a fungus species in the genus Omphalotus. The type collection was found by Murrill on July 26, 1944 in Gainesville, Florida. It has also been recorded from Texas. [1]

Atromentin and thelephoric acid are chemical compounds found in cultures of C. subilludens.[2] Atromentin is an effective anticoagulant, and similar in biological activity to the well-known anticoagulant heparin.[3] Atromentin also possesses antibacterial activity, inhibiting the enzyme enoyl-acyl carrier protein reductase (essential for the biosynthesis of fatty acids) in the bacteria Streptococcus pneumoniae.[4]

It also produces illudoids.[5]

References[edit]

  1. ^ Murrill, W.A., 1945, Quarterly Journal of the Florida Academy of Science 8(2): 198
  2. ^ Sullivan, G.; Garrett, R. D.; Lenehan, R. F. (1971). "Occurrence of atromentin and thelephoric acid in cultures ofclitocybe subilludens". Journal of Pharmaceutical Sciences. 60 (11): 1727–9. doi:10.1002/jps.2600601134. PMID 4332377. 
  3. ^ Khanna JM, Malone MH, Euler KL, Brady LR (1965). "Atromentin – anticoagulant from Hydnellum diabolus". Journal of Pharmaceutical Science. 54 (7): 1016–20. doi:10.1002/jps.2600540714. PMID 5862512. 
  4. ^ Zheng CJ, Sohn MJ, Kim WG (2006). "Atromentin and leucomelone, the first inhibitors specific to enoyl-ACP reductase (FabK) of Streptococcus pneumoniae". Journal of Antibiotics. 59 (12): 808–12. doi:10.1038/ja.2006.108. PMID 17323650. 
  5. ^ Illudoids from Omphalotus olivascens and Clitocybe subilludens. Nair M. S. R., Carey S. T. and Rogerson C. T., Mycologia, 1983, vol. 75, no5, pages 920-922, INIST:9415717

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