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Cucurbitadienol synthase (EC5.4.99.33, CPQ (gene), (S)-2,3-epoxysqualene mutase (cyclizing, cucurbitadienol-forming)) is an enzyme with systematic name(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, cucurbitadienol-forming).[1] This enzyme catalyses the following chemical reaction
^Shibuya M, Adachi S, Ebizuka Y (2004). "Cucurbitadienol synthase, the first committed enzyme for cucurbitacin biosynthesis, is a distinct enzyme from cycloartenol synthase for phytosterol biosynthesis". Tetrahedron. 60: 6995–7003. doi:10.1016/j.tet.2004.04.088.
