Cytochalasin E
Appearance
Identifiers | |
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3D model (JSmol)
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ChemSpider | |
ECHA InfoCard | 100.048.018 |
EC Number |
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PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C28H33NO7 | |
Molar mass | 495.572 g·mol−1 |
Density | 1.309 g/ml |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards
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Toxic |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Cytochalasin E, a member of the cytochalasin group, is an inhibitor of actin polymerization in blood platelets. It inhibits angiogenesis and tumor growth. Unlike cytochalasin A and cytochalasin B, it does not inhibit glucose transport.
Because of its antiangiogenic effect, cytochalasin E is a potential drug for age-related macular degeneration, a kind of blindness caused by an abnormal proliferation of blood vessels in the eye.[2]
References
External pages
Cytochalasin E from Fermentek
Cytochalasin E from Cayman Chemical