DNASE1L1

DNASE1L1
Identifiers
Aliases	DNASE1L1, DNAS1L1, DNASEX, DNL1L, G4.8, XIB, deoxyribonuclease I-like 1, deoxyribonuclease 1 like 1
External IDs	OMIM: 300081; MGI: 109628; HomoloGene: 4896; GeneCards: DNASE1L1; OMA:DNASE1L1 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	154,412,112 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	73,325,943 bp
RNA expression pattern
	Top expressed in
	muscle of thigh; ; gastrocnemius muscle; ; glutes; ; Skeletal muscle tissue of biceps brachii; ; Skeletal muscle tissue of rectus abdominis; ; vastus lateralis muscle; ; apex of heart; ; stromal cell of endometrium; ; triceps brachii muscle; ; tendon of biceps brachii;
	Top expressed in
	quadriceps femoris muscle; ; muscle of thigh; ; skeletal muscle tissue; ; bone marrow; ; zone of skin; ; esophagus; ; duodenum; ; granulocyte; ; lip; ; colon;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; nuclease activity; endonuclease activity; hydrolase activity; deoxyribonuclease activity; deoxyribonuclease I activity;
Cellular component	endoplasmic reticulum; extracellular region; specific granule lumen; nucleus;
Biological process	DNA metabolic process; DNA catabolic process; nucleic acid phosphodiester bond hydrolysis; neutrophil degranulation; DNA catabolic process, endonucleolytic;
	Sources:Amigo / QuickGO
Orthologs
	1774
	69537
	ENSG00000013563
	ENSMUSG00000019088
	P49184
	Q9D7J6
	NM_001009932; NM_001009933; NM_001009934; NM_001303620; NM_006730
	NM_001172154; NM_027109; NM_001370787
	NP_001009932; NP_001009933; NP_001009934; NP_001290549; NP_006721
	NP_001165625; NP_081385; NP_001357716
	Wikidata
View/Edit Human	View/Edit Mouse

Deoxyribonuclease-1-like 1 is an enzyme that in humans is encoded by the DNASE1L1 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000013563 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000019088 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Parrish JE, Ciccodicola A, Wehhert M, Cox GF, Chen E, Nelson DL (Feb 1996). "A muscle-specific DNase I-like gene in human Xq28". Hum Mol Genet. 4 (9): 1557–64. doi:10.1093/hmg/4.9.1557. PMID 8541839.
^ Pergolizzi R, Appierto V, Bosetti A, DeBellis GL, Rovida E, Biunno I (Jul 1996). "Cloning of a gene encoding a DNase I-like endonuclease in the human Xq28 region". Gene. 168 (2): 267–70. doi:10.1016/0378-1119(95)00741-5. PMID 8654957.
^ "Entrez Gene: DNASE1L1 deoxyribonuclease I-like 1".

References

Further reading