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DTL (gene)

From Wikipedia, the free encyclopedia
DTL
Identifiers
AliasesDTL, CDT2, DCAF2, L2RAMP, denticleless E3 ubiquitin protein ligase homolog
External IDsOMIM: 610617; MGI: 1924093; HomoloGene: 32313; GeneCards: DTL; OMA:DTL - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001286229
NM_001286230
NM_016448

NM_029766
NM_001305233

RefSeq (protein)

NP_001273158
NP_001273159
NP_057532

NP_001292162
NP_084042

Location (UCSC)Chr 1: 212.04 – 212.11 MbChr 1: 191.27 – 191.31 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Denticleless protein homolog is a protein that in humans is encoded by the DTL gene.[5][6]

Interactions

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DTL (gene) has been shown to interact with P21.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000143476Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000037474Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Cheung WM, Chu AH, Chu PW, Ip NY (May 2001). "Cloning and expression of a novel nuclear matrix-associated protein that is regulated during the retinoic acid-induced neuronal differentiation". J Biol Chem. 276 (20): 17083–91. doi:10.1074/jbc.M010802200. PMID 11278750.
  6. ^ "Entrez Gene: DTL denticleless homolog (Drosophila)".
  7. ^ Abbas T, Sivaprasad U, Terai K, Amador V, Pagano M, Dutta A (Sep 2008). "PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex". Genes Dev. 22 (18): 2496–506. doi:10.1101/gad.1676108. PMC 2546691. PMID 18794347.

Further reading

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