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A dehydrogenase (also called DHO in the literature) is an enzyme belonging to the group of oxidoreductases that oxidizes a substrate by a reduction reaction that transfers one or more hydrides (H) to an electron acceptor, usually NAD+/NADP+ or a flavin coenzyme such as FAD or FMN.

Oxidoreductases, in general, catalyze oxidation and reduction reactions. Any enzyme that transfers an electron from one molecule to another is considered an oxidoreductase. These enzymes fall into six categories: oxygenases, reductases, peroxidases, oxidases, hydroxylases, and dehydrogenases. Most oxidoreductase enzymes can be classified using the name dehydrogenase, accepted nomenclature being "donor dehydrogenase," where the donor is the molecule giving up an electron.[1]


TCA cycle examples:


  1. ^ "Enzymes: Types of enzyme - Biochemistry | Fastbleep". Retrieved 2016-02-02. 
  2. ^ Međedović S., Maslić E., Hadžiselimović R. (2000): Biologija 2. Svjetlost, Sarajevo, ISBN 9958-10-222-6.
  3. ^ Kornberg A. (1989): For the love of enzymes – The Odyssay of a biochemist. Harvard University Press, Cambridge (Mass.), London,ISBN 0-674-30775-5, ISBN 0-674-30776-3.
  4. ^ Graeme K. Hunter G. K. (2000): Vital Forces. The discovery of the molecular basis of life. Academic Press, London, ISBN 0-12-361811-8.
  5. ^ Nelson D. L., Michael M. Cox M. M. (2013): Lehninger Principles of Biochemistry. W. H. Freeman, 2013.ISBN 978-1-4641-0962-1.