Dermatopathic lymphadenopathy

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Micrograph showing dermatopathic lymphadenopathy with the characteristic paracortical histiocytosis and melanin-laden macrophages. H&E stain.

In pathology, dermatopathic lymphadenopathy, also dermatopathic lymphadenitis, is lymph node pathology due to skin disease.

Associations/differential diagnosis[edit]


Dermatopathic lymphadenopathy is diagnosed by a lymph node biopsy. It has a characteristic pattern of histomorphology and immunohistochemical staining:

  • Paracortical histiocytosis
  • Melanin-laden macrophages
  • Eosinophils
  • Plasma cells (medulla of lymph node)


The treatment is based on the underlying cause.

See also[edit]


  1. ^ a b Lee, SW.; Park, MC.; Kim, H.; Park, YB.; Lee, SK. "Dermatopathic lymphadenopathy in a patient with adult onset Still's disease.". Clin Exp Rheumatol. 25 (2): 312–14. PMID 17543161. 

External links[edit]