showing dermatopathic lymphadenopathy with the characteristic paracortical histiocytosis and melanin
-laden macrophages. H&E stain
In pathology, dermatopathic lymphadenopathy, also dermatopathic lymphadenitis, is lymph node pathology due to skin disease.
Dermatopathic lymphadenopathy is diagnosed by a lymph node biopsy. It has a characteristic pattern of histomorphology and immunohistochemical staining:
- Paracortical histiocytosis
- Melanin-laden macrophages
- Plasma cells (medulla of lymph node)
The treatment is based on the underlying cause.
- ^ a b Lee, SW.; Park, MC.; Kim, H.; Park, YB.; Lee, SK. "Dermatopathic lymphadenopathy in a patient with adult onset Still's disease.". Clin Exp Rheumatol. 25 (2): 312–14. PMID 17543161.