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Dimetapp is a brand of over-the-counter cold and allergy medicines manufactured by Pfizer (formerly Wyeth). At one point, Dimetapp as a household word referred to a single combination preparation marketed to relieve symptoms of the common cold, containing brompheniramine (an antihistamine) and phenylephrine (decongestant replacing the formerly used pseudoephedrine, which itself replaced phenylpropanolamine). Variants were created, including Dimetapp DM with the addition of dextromethorphan (an antitussive or cough suppressant). Dimetapp Elixir and Colour Free Elixir are intended to relieve nasal congestion, runny nose, itchy watery eyes and sneezing, whereas Dimetapp DM and Dimetapp DM Colour Free Elixir are intended for colds with dry coughs and also to treat whooping cough. Early Dimetapp liquid products were characterized by being flavoured like a strong grape candy.

Like many over-the-counter medications, Dimetapp relies on marketing and branding as differentiators of otherwise similar (often identical) branded and unbranded medications to maintain their premium pricing. Additionally, the actual medications are subject to remarketing in other brands. As an example, "Children's Dimetapp ND" is a 10 mg orally disintegrating loratadine tablet with a "cool blast" flavour additive. The same product with a "Citrus Burst" flavour additive was also manufactured and distributed by Wyeth but branded and marketed as "Alavert" (not "children's").

Dimetapp was acquired by Pfizer in the 2009 acquisition of Wyeth.

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