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Horn was born in Athens in 1921, the son of playwright Pantelis Horn (himself descended from an Austrian father and Greek mother), and Euterpi, a Greek. He studied at the Drama at the National Theater School of Greece, where he made his stage debut in 1941. During his career, he co-operated many times with the Greek National Theater and made personal stage troops with actors such as Mary Aroni, Alekos Alexandrakis and Ellie Lambeti. The latter was also his companion from 1953 to 1958.
From an early stage he developed a reputation as "the best actor of his generation," performing many classics such as "Diary of a Madman" by Nikolai Gogol, "Richard III" by William Shakespeare, "Dom Juan" by Molière, "Enrico IV" by Luigi Pirandello to critical acclaim.
Of lesser importance to him was his screen work; as he disliked cinema only starring in ten films. His most notable films were The Counterfeit Coin (1954), and A Girl in Black (1956). He later married shipping heiress Anna Goulandri, and became the first director of the Greek State Radio and Television after the restoration of democracy. He died on January 16, 1998, of cancer.
- Athens by Night - I Athina tin nychta 1962
- Woe to the Young - Alimono stous neous, 1961
- A Thief's First Chance - Mia tou klefti, 1960
- We Have Only One Life - Mia zoi tin echoume, 1958
- The Girl in Black - To Koritsi me ta mavra, 1956
- The Counterfeit Sovereign - Kalpiki lira, 1955
- Windfall in Athens - Kyriakatiko xypnima, 1954
- The Drunkard - Methistakas, 1950
- Applause - Hirokrotimata, 1944
- Voice of the Heart - I Foni tis kardias, 1943