ERO1LB

ERO1B
Identifiers
Aliases	ERO1B, ERO1LB, Ero1beta, endoplasmic reticulum oxidoreductase beta, endoplasmic reticulum oxidoreductase 1 beta
External IDs	OMIM: 615437; MGI: 1914725; HomoloGene: 8740; GeneCards: ERO1B; OMA:ERO1B - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	236,282,019 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	12,626,285 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; islet of Langerhans; ; secondary oocyte; ; body of stomach; ; corpus epididymis; ; beta cell; ; endothelial cell; ; fundus; ; testicle; ; right lobe of liver;
	Top expressed in
	islet of Langerhans; ; lacrimal gland; ; seminal vesicula; ; spermatocyte; ; spermatid; ; salivary gland; ; pyloric antrum; ; submandibular gland; ; parotid gland; ; left lobe of liver;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	unfolded protein binding; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; oxidoreductase activity; protein binding; protein-disulfide reductase activity; protein disulfide isomerase activity;
Cellular component	endoplasmic reticulum; membrane; endoplasmic reticulum membrane;
Biological process	insulin processing; 4-hydroxyproline metabolic process; extracellular matrix organization; protein folding; protein maturation by protein folding; glucose homeostasis; cell redox homeostasis; protein folding in endoplasmic reticulum;
	Sources:Amigo / QuickGO
Orthologs
	56605
	67475
	ENSG00000086619
	ENSMUSG00000057069
	Q86YB8
	Q8R2E9
	NM_019891
	NM_026184
	NP_063944
	NP_080460
	Wikidata
View/Edit Human	View/Edit Mouse

ERO1-like protein beta is a protein that in humans is encoded by the ERO1LB gene.^[5]^[6]

Template:PBB Summary

Interactions

ERO1LB has been shown to interact with P4HB.^[7]^[8]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000086619 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000057069 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Pagani M, Fabbri M, Benedetti C, Fassio A, Pilati S, Bulleid NJ, Cabibbo A, Sitia R (Sep 2000). "Endoplasmic reticulum oxidoreductin 1-lbeta (ERO1-Lbeta), a human gene induced in the course of the unfolded protein response". J Biol Chem. 275 (31): 23685–92. doi:10.1074/jbc.M003061200. PMID 10818100.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: ERO1LB ERO1-like beta (S. cerevisiae)".
^ Anelli, Tiziana; Alessio Massimo; Mezghrani Alexandre; Simmen Thomas; Talamo Fabio; Bachi Angela; Sitia Roberto (Feb 2002). "ERp44, a novel endoplasmic reticulum folding assistant of the thioredoxin family". EMBO J. 21 (4). England: 835–44. doi:10.1093/emboj/21.4.835. ISSN 0261-4189. PMC 125352. PMID 11847130. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)
^ Mezghrani, A; Fassio A; Benham A; Simmen T; Braakman I; Sitia R (Nov 2001). "Manipulation of oxidative protein folding and PDI redox state in mammalian cells". EMBO J. 20 (22). England: 6288–96. doi:10.1093/emboj/20.22.6288. ISSN 0261-4189. PMC 125306. PMID 11707400. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)

Interactions

References

Further reading