Elaine Mardis

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Elaine Mardis
Born (1962-09-28) September 28, 1962 (age 54)[citation needed]
Institutions McDonnell Genome Institute
Washington University School of Medicine
University of Oklahoma
Bio-Rad Laboratories

Elaine R Mardis (born September 28, 1962) is an American Professor of Genetics, with an adjunct appointment in the Department of Molecular microbiology at Washington University in St. Louis[1] and Co-Director of the McDonnell Genome Institute. Dr. Mardis is also the Director of the McDonnell Genome Institute's Technology Development group, a group that researches, tests and implements new sequencing technologies.[2][3][4] Using next-generation sequencing technology,[5] her group is developing applications and processes for use in the McDonnell Genome Institute’s sequencing projects.[6] Dr. Mardis also helped lead the group that sequenced the first whole cancer genome[7] and has since gone on to sequence many other cancer genomes to determine the genetic changes that may lead to cancer.[8][9] Other research Dr. Mardis participates in includes human genetic variation[10] and genomics education.[11]

Dr. Mardis serves as chair of the Basic and Translational Sciences Committee for the American College of Surgeons Oncology Group (ACOSOG).[12] In 2011, she received the Distinguished Alumni Award from the University of Oklahoma College of Arts and Sciences.[13] She also received the Scripps Translational Research award for her work on cancer genomics in 2010.[14]

In 2015, Dr. Mardis helped launch an open access, precision medicine journal, Molecular Case Studies, in conjunction with Cold Spring Harbor Laboratory Press.[15] She currently serves as Editor-in-Chief.

Prior to joining the Washington University faculty, she was a senior research scientist at Bio-Rad Laboratories in Hercules, California. She received her Bachelor of Science degree in 1984 and her Ph.D. in 1989 from the University of Oklahoma.[16]

Awards and honors[edit]


  1. ^ WUSTL Bio
  2. ^ Mardis, E. R. (2011). "A decade's perspective on DNA sequencing technology". Nature. 470 (7333): 198–203. doi:10.1038/nature09796. PMID 21307932. 
  3. ^ McDonnell Institute Bio
  4. ^ Lander, E. S.; Linton, M.; Birren, B.; Nusbaum, C.; Zody, C.; Baldwin, J.; Devon, K.; Dewar, K.; Doyle, M.; Fitzhugh, W.; Funke, R.; Gage, D.; Harris, K.; Heaford, A.; Howland, J.; Kann, L.; Lehoczky, J.; Levine, R.; McEwan, P.; McKernan, K.; Meldrim, J.; Mesirov, J. P.; Miranda, C.; Morris, W.; Naylor, J.; Raymond, C.; Rosetti, M.; Santos, R.; Sheridan, A.; et al. (Feb 2001). "Initial sequencing and analysis of the human genome". Nature. 409 (6822): 860–921. doi:10.1038/35057062. ISSN 0028-0836. PMID 11237011. 
  5. ^ Mardis, E. R. (2006). "Anticipating the 1,000 dollar genome". Genome Biology. 7 (7): 112. doi:10.1186/gb-2006-7-7-112. PMC 1779559Freely accessible. PMID 17224040. 
  6. ^ "Q&A: Wash U's Elaine Mardis on Testing New Sequencing Tech for a Large Genome Center." GenomeWeb In Sequence. 17 February 2009.
  7. ^ "Scientists Decode Cancer Cell DNA." CBS Evening News. 6 November 2008.
  8. ^ Mardis, E. R.; Ding, L.; Dooling, D. J.; Larson, D. E.; McLellan, M. D.; Chen, K.; Koboldt, D. C.; Fulton, R. S.; Delehaunty, K. D.; McGrath, S. D.; Fulton, L. A.; Locke, D. P.; Magrini, V. J.; Abbott, R. M.; Vickery, T. L.; Reed, J. S.; Robinson, J. S.; Wylie, T.; Smith, S. M.; Carmichael, L.; Eldred, J. M.; Harris, C. C.; Walker, J.; Peck, J. B.; Du, F.; Dukes, A. F.; Sanderson, G. E.; Brummett, A. M.; Clark, E.; McMichael, J. F. (2009). "Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome". New England Journal of Medicine. 361 (11): 1058–1066. doi:10.1056/NEJMoa0903840. PMC 3201812Freely accessible. PMID 19657110. 
  9. ^ "Cancer gene complexity revealed" BBC News. 7 August 2009.
  10. ^ Steering Committee Member, 1000 Genomes Project
  11. ^ Member, Genomics Education Partnership
  12. ^ Chair, ACOSOG Basic and Translational Sciences Committee. American College of Surgeons Oncology Group. 2010.
  13. ^ Distinguished Alumni Award. University of Oklahoma. 2011.
  14. ^ Scripps Genomic Medicine award. Scripps Research Institute. 2010.
  15. ^ DeBerardinis, Ralph J.; Mardis, Elaine R. (2015-10-01). "From "N of 1" to N of more". Molecular Case Studies. 1 (1): a000521. doi:10.1101/mcs.a000521. ISSN 2373-2873. 
  16. ^ "Q&A: Wash U's Elaine Mardis on Testing New Sequencing Tech for a Large Genome Center" GenomeWeb In Sequence. 17 February 2009.

External links[edit]