|Born||citation needed]September 28, 1962 [|
|Institutions||McDonnell Genome Institute
Washington University School of Medicine
University of Oklahoma
Elaine R Mardis (born September 28, 1962) is an American Professor of Genetics, with an adjunct appointment in the Department of Molecular microbiology at Washington University in St. Louis and Co-Director of the McDonnell Genome Institute. Dr. Mardis is also the Director of the McDonnell Genome Institute's Technology Development group, a group that researches, tests and implements new sequencing technologies. Using next-generation sequencing technology, her group is developing applications and processes for use in the McDonnell Genome Institute’s sequencing projects. Dr. Mardis also helped lead the group that sequenced the first whole cancer genome and has since gone on to sequence many other cancer genomes to determine the genetic changes that may lead to cancer. Other research Dr. Mardis participates in includes human genetic variation and genomics education.
Dr. Mardis serves as chair of the Basic and Translational Sciences Committee for the American College of Surgeons Oncology Group (ACOSOG). In 2011, she received the Distinguished Alumni Award from the University of Oklahoma College of Arts and Sciences. She also received the Scripps Translational Research award for her work on cancer genomics in 2010.
In 2015, Dr. Mardis helped launch an open access, precision medicine journal, Molecular Case Studies, in conjunction with Cold Spring Harbor Laboratory Press. She currently serves as Editor-in-Chief.
Prior to joining the Washington University faculty, she was a senior research scientist at Bio-Rad Laboratories in Hercules, California. She received her Bachelor of Science degree in 1984 and her Ph.D. in 1989 from the University of Oklahoma.
Awards and honors
- Distinguished Alumni Award, University of Oklahoma, 2011
- Scripps Genomic Medicine Award, Scripps Research Institute, 2010
- Editor-in-Chief, Cold Spring Harbor Molecular Case Studies
- Monitoring Editor, Disease Models & Mechanisms
- Editorial Board, Genome Biology
- Editorial Board, Genome Research
- Chair, Basic and Translational Science Committee, American College of Surgeons Oncology Group
- WUSTL Bio
- Mardis, E. R. (2011). "A decade's perspective on DNA sequencing technology". Nature. 470 (7333): 198–203. doi:10.1038/nature09796. PMID 21307932.
- McDonnell Institute Bio
- Lander, E. S.; Linton, M.; Birren, B.; Nusbaum, C.; Zody, C.; Baldwin, J.; Devon, K.; Dewar, K.; Doyle, M.; Fitzhugh, W.; Funke, R.; Gage, D.; Harris, K.; Heaford, A.; Howland, J.; Kann, L.; Lehoczky, J.; Levine, R.; McEwan, P.; McKernan, K.; Meldrim, J.; Mesirov, J. P.; Miranda, C.; Morris, W.; Naylor, J.; Raymond, C.; Rosetti, M.; Santos, R.; Sheridan, A.; et al. (Feb 2001). "Initial sequencing and analysis of the human genome". Nature. 409 (6822): 860–921. doi:10.1038/35057062. ISSN 0028-0836. PMID 11237011.
- Mardis, E. R. (2006). "Anticipating the 1,000 dollar genome". Genome Biology. 7 (7): 112. doi:10.1186/gb-2006-7-7-112. PMC . PMID 17224040.
- "Q&A: Wash U's Elaine Mardis on Testing New Sequencing Tech for a Large Genome Center." GenomeWeb In Sequence. 17 February 2009.
- "Scientists Decode Cancer Cell DNA." CBS Evening News. 6 November 2008.
- Mardis, E. R.; Ding, L.; Dooling, D. J.; Larson, D. E.; McLellan, M. D.; Chen, K.; Koboldt, D. C.; Fulton, R. S.; Delehaunty, K. D.; McGrath, S. D.; Fulton, L. A.; Locke, D. P.; Magrini, V. J.; Abbott, R. M.; Vickery, T. L.; Reed, J. S.; Robinson, J. S.; Wylie, T.; Smith, S. M.; Carmichael, L.; Eldred, J. M.; Harris, C. C.; Walker, J.; Peck, J. B.; Du, F.; Dukes, A. F.; Sanderson, G. E.; Brummett, A. M.; Clark, E.; McMichael, J. F. (2009). "Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome". New England Journal of Medicine. 361 (11): 1058–1066. doi:10.1056/NEJMoa0903840. PMC . PMID 19657110.
- "Cancer gene complexity revealed" BBC News. 7 August 2009.
- Steering Committee Member, 1000 Genomes Project
- Member, Genomics Education Partnership
- Chair, ACOSOG Basic and Translational Sciences Committee. American College of Surgeons Oncology Group. 2010.
- Distinguished Alumni Award. University of Oklahoma. 2011.
- Scripps Genomic Medicine award. Scripps Research Institute. 2010.
- DeBerardinis, Ralph J.; Mardis, Elaine R. (2015-10-01). "From "N of 1" to N of more". Molecular Case Studies. 1 (1): a000521. doi:10.1101/mcs.a000521. ISSN 2373-2873.
- "Q&A: Wash U's Elaine Mardis on Testing New Sequencing Tech for a Large Genome Center" GenomeWeb In Sequence. 17 February 2009.
- McDonnell Institute Bio
- [Author] PubMed Citations
- "Elaine Mardis and Richard Wilson: Taking Cancer's Genetic Measure." US News & World Report. 30 June 2009.
- "Revolutionizing cancer care with next-generation sequencing: an interview with Elaine Mardis." Disease Models & Mechanisms 2014 7: 313-317; doi: 10.1242/dmm.015396
- "Genetic Clues to Cancer's Spread." Technology Review. 14 April 2010.
- "Washington University Team Sequences AML Relapse Tumor." GenomeWeb Daily News. 12 May 2010.
- Nature Podcast. 15 April 2010.
- "A Conversation about Sequencing Cancer Genomes with Dr. Elaine Mardis." NCI Cancer Bulletin. 26 January 2010.