Ethambutol/isoniazid/pyrazinamide/rifampicin
| Combination of | |
|---|---|
| Ethambutol | Anti-tuberculosis medication |
| Isoniazid | Anti-tuberculosis medication |
| Pyrazinamide | Anti-tuberculosis medication |
| Rifampicin | Anti-tuberculosis medication |
| Clinical data | |
| Trade names | Voractiv, Rimstar, others |
| ATC code | |
| Identifiers | |
| ChemSpider |
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Ethambutol/isoniazid/pyrazinamide/rifampicin, also known as ethambutol/isoniazid/pyrazinamide/rifampin, is a medication used for tuberculosis.[1] It is a fixed dose combination of ethambutol, isoniazid, pyrazinamide, and rifampicin.[1] It is used either alone or with other antituberculosis medication.[1] It is taken by mouth.[1]
Side effects are those of the underlying medications.[1] Pyridoxine may be used to decrease the risk of numbness.[2] It is not recommended in people with liver problems or severe kidney problems.[3] Use may not be suitable in children.[1] It is unclear if use during pregnancy is safe.[3]
It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[4] In the United Kingdom it costs the NHS 98.75 pounds for a typical month of medication as of 2015.[2] It is sold under the brand names Voractiv and Rimstar in the UK.[3]
References
- ^ a b c d e f WHO Model Formulary 2008 (PDF). World Health Organization. 2009. p. 142. ISBN 9789241547659. Archived (PDF) from the original on 13 December 2016. Retrieved 8 December 2016.
- ^ a b British national formulary : BNF 69 (69 ed.). British Medical Association. 2015. p. 403. ISBN 9780857111562.
- ^ a b c "Rimstar Film-coated Tablet / Voractiv Film-coated Tablet - Summary of Product Characteristics (SPC) - (eMC)". www.medicines.org.uk. February 2016. Archived from the original on 20 December 2016. Retrieved 18 December 2016.
- ^ "WHO Model List of Essential Medicines (19th List)" (PDF). World Health Organization. April 2015. Archived (PDF) from the original on 13 December 2016. Retrieved 8 December 2016.
