FBXO6

FBXO6
Identifiers
Aliases	FBXO6, FBG2, FBS2, FBX6, Fbx6b, F-box protein 6
External IDs	OMIM: 605647; MGI: 1354743; HomoloGene: 9274; GeneCards: FBXO6; OMA:FBXO6 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	11,674,354 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	148,236,597 bp
RNA expression pattern
	Top expressed in
	monocyte; ; gastrocnemius muscle; ; bronchial epithelial cell; ; blood; ; right lobe of liver; ; right adrenal gland; ; right uterine tube; ; pancreatic ductal cell; ; appendix; ; left adrenal gland;
	Top expressed in
	urinary bladder; ; adrenal gland; ; muscle tissue; ; skeletal muscle tissue; ; quadriceps femoris muscle; ; placenta; ; white adipose tissue; ; lip; ; ileum; ; islet of Langerhans;
	More reference expression data
	n/a
Gene ontology
Molecular function	ubiquitin protein ligase activity; carbohydrate binding; ubiquitin-protein transferase activity; protein binding;
Cellular component	cytoplasm; SCF ubiquitin ligase complex; endoplasmic reticulum quality control compartment; cytosol;
Biological process	cellular response to DNA damage stimulus; DNA damage checkpoint signaling; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; response to unfolded protein; DNA repair; protein ubiquitination; proteolysis; ubiquitin-dependent ERAD pathway; glycoprotein catabolic process; protein polyubiquitination; post-translational protein modification;
	Sources:Amigo / QuickGO
Orthologs
	26270
	50762
	ENSG00000116663
	ENSMUSG00000055401
	Q9NRD1
	Q9QZN4
	NM_018438
	NM_001163704; NM_001163705; NM_001163706; NM_001163707; NM_015797
	NP_060908
	NP_001157176; NP_001157177; NP_001157178; NP_001157179; NP_056612
	Wikidata
View/Edit Human	View/Edit Mouse

F-box only protein 6 is a protein that in humans is encoded by the FBXO6 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000116663 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000055401 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Cenciarelli C, Chiaur DS, Guardavaccaro D, Parks W, Vidal M, Pagano M (Dec 1999). "Identification of a family of human F-box proteins". Curr Biol. 9 (20): 1177–9. doi:10.1016/S0960-9822(00)80020-2. PMID 10531035.
^ Ilyin GP, Rialland M, Pigeon C, Guguen-Guillouzo C (Nov 2000). "cDNA cloning and expression analysis of new members of the mammalian F-box protein family". Genomics. 67 (1): 40–7. doi:10.1006/geno.2000.6211. PMID 10945468.
^ "Entrez Gene: FBXO6 F-box protein 6".

References

Further reading