FLRT3

FLRT3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5CMN, 5CMP
Identifiers
Aliases	FLRT3, HH21, fibronectin leucine rich transmembrane protein 3
External IDs	OMIM: 604808; MGI: 1918686; HomoloGene: 8322; GeneCards: FLRT3; OMA:FLRT3 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	14,337,614 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	140,513,389 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; lower lobe of lung; ; pericardium; ; Brodmann area 23; ; middle temporal gyrus; ; renal medulla; ; visceral pleura; ; germinal epithelium; ; jejunal mucosa; ; hair follicle;
	Top expressed in
	genital tubercle; ; hand; ; abdominal wall; ; tail of embryo; ; hair follicle; ; mandibular prominence; ; otolith organ; ; ganglionic eminence; ; maxillary prominence; ; olfactory tubercle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein-macromolecule adaptor activity; protein homodimerization activity; fibroblast growth factor receptor binding; protein kinase inhibitor activity; protein binding; chemorepellent activity;
Cellular component	cytoplasm; axon terminus; integral component of membrane; synaptic membrane; cell projection; endoplasmic reticulum membrane; membrane; cell-cell junction; focal adhesion; axonal growth cone; integral component of plasma membrane; extracellular region; axon; endoplasmic reticulum; extracellular space; cytosol; plasma membrane; cell junction; extracellular matrix; glutamatergic synapse; integral component of postsynaptic membrane;
Biological process	negative chemotaxis; negative regulation of protein kinase activity; cytokine-mediated signaling pathway; head development; neuron projection extension; axon guidance; multicellular organism development; heart development; cell adhesion; response to axon injury; embryonic morphogenesis; proepicardium cell migration involved in pericardium morphogenesis; synapse assembly; neuron projection development; negative regulation of receptor signaling pathway via JAK-STAT; positive regulation of synapse assembly; fibroblast growth factor receptor signaling pathway; cell-cell adhesion via plasma-membrane adhesion molecules; synaptic membrane adhesion;
	Sources:Amigo / QuickGO
Orthologs
	23767
	71436
	ENSG00000125848
	ENSMUSG00000051379
	Q9NZU0
	Q8BGT1
	NM_013281; NM_198391
	NM_001172160; NM_178382
	NP_037413; NP_938205
	NP_001165631; NP_848469
	Wikidata
View/Edit Human	View/Edit Mouse

Leucine-rich repeat transmembrane protein FLRT3 is a protein that in humans is encoded by the FLRT3 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000125848 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000051379 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lacy SE, Bonnemann CG, Buzney EA, Kunkel LM (Mar 2000). "Identification of FLRT1, FLRT2, and FLRT3: a novel family of transmembrane leucine-rich repeat proteins". Genomics. 62 (3): 417–26. doi:10.1006/geno.1999.6033. PMID 10644439.
^ "Entrez Gene: FLRT3 fibronectin leucine rich transmembrane protein 3".

References

Further reading