Far upstream element-binding protein 1

FUBP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1J4W, 2KXH, 4LIJ
Identifiers
Aliases	FUBP1, FBP, FUBP, hDH V, far upstream element binding protein 1
External IDs	OMIM: 603444; MGI: 1196294; HomoloGene: 48253; GeneCards: FUBP1; OMA:FUBP1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	77,979,110 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	151,942,463 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; Achilles tendon; ; right uterine tube; ; left lobe of thyroid gland; ; right lobe of thyroid gland; ; canal of the cervix; ; lymph node; ; tibial nerve; ; anterior pituitary; ; right lung;
	Top expressed in
	maxillary prominence; ; somite; ; abdominal wall; ; ganglionic eminence; ; thymus; ; hand; ; primitive streak; ; dermis; ; yolk sac; ; cerebellar cortex;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; nucleic acid binding; single-stranded DNA binding; DNA-binding transcription factor activity; DNA binding; RNA binding;
Cellular component	nucleus; nucleoplasm;
Biological process	positive regulation of gene expression; regulation of transcription, DNA-templated; transcription by RNA polymerase II; transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	8880
	51886
	ENSG00000162613
	ENSMUSG00000028034
	Q96AE4
	Q91WJ8
	NM_001303433; NM_003902; NM_001376055; NM_001376056; NM_001376057
NM_057172; NM_001355366; NM_001355367; NM_001355368; NM_001355369;
	NM_001355370; NM_001355371; NM_001355372; NM_001355373; NM_001355374
	NP_001290362; NP_003893; NP_001362984; NP_001362985; NP_001362986
NP_476513; NP_001342295; NP_001342296; NP_001342297; NP_001342298;
	NP_001342299; NP_001342300; NP_001342301; NP_001342302; NP_001342303
	Wikidata
View/Edit Human	View/Edit Mouse

Far upstream element-binding protein 1 is a protein that in humans is encoded by the FUBP1 gene.^[5]^[6]

Template:PBB Summary

Interactions

Far upstream element-binding protein 1 has been shown to interact with MAPK14^[7] and SMN1.^[8]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000162613 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028034 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Duncan R, Bazar L, Michelotti G, Tomonaga T, Krutzsch H, Avigan M, Levens D (April 1994). "A sequence-specific, single-strand binding protein activates the far upstream element of c-myc and defines a new DNA-binding motif". Genes Dev. 8 (4): 465–80. doi:10.1101/gad.8.4.465. PMID 8125259.
^ "Entrez Gene: FUBP1 far upstream element (FUSE) binding protein 1".
^ Kim, Min Jung; Park Bum-Joon; Kang Young-Sun; Kim Hyoung June; Park Jae-Hyun; Kang Jung Woo; Lee Sang Won; Han Jung Min; Lee Han-Woong; Kim Sunghoon (July 2003). "Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation". Nat. Genet. 34 (3). United States: 330–6. doi:10.1038/ng1182. ISSN 1061-4036. PMID 12819782. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)
^ Williams, B Y; Hamilton S L; Sarkar H K (March 2000). "The survival motor neuron protein interacts with the transactivator FUSE binding protein from human fetal brain". FEBS Lett. 470 (2). NETHERLANDS: 207–10. doi:10.1016/S0014-5793(00)01320-X. ISSN 0014-5793. PMID 10734235. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help)

Interactions

References

Further reading