Fluorocitric acid

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Fluorocitric acid
Fluorocitric acid.svg
IUPAC name
3-C-Carboxy-2,4-dideoxy-2-fluoropentaric acid
Other names
2-Fluorocitric acid; 2-Fluorocitrate; 1-Fluoro-2-hydroxypropane-1,2,3-tricarboxylic acid
3D model (JSmol)
Molar mass 210.11 g·mol−1
Appearance Odorless, white crystals
Density 1.37
Melting point 35.2°C
Boiling point 165°C
Main hazards GHS-pictogram-skull.svgGHS-pictogram-pollu.svg
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Fluorocitric acid is a fluorinated carboxylic acid derived from citric acid by substitution of one hydrogen by a fluorine atom. The appropriate anion is called fluorocitrate. It is a metabolite of fluoroacetic acid and is very toxic because it is not processable using aconitase in the citrate cycle (where fluorocitrate takes place of citrate as the substrate). The enzyme is inhibited and the cycle stops working.[1]

See also[edit]


  1. ^ Horák, J.; Linhart, I.; Klusoň, P. (2004). Úvod do toxikologie a ekologie pro chemiky (in Czech) (1st ed.). Prague: VŠCHT v Praze. ISBN 80-7080-548-X. 

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