Fluorodopa

Fluorodopa
Clinical data
Other names	6-fluoro-L-DOPA; FDOPA
Identifiers
	IUPAC name 2-fluoro-5-hydroxy-L-tyrosine;
CAS Number	75290-51-6;
ChemSpider	96897;
UNII	6WIZ27OUZ9;
CompTox Dashboard (EPA)	DTXSID90226257 ;
Chemical and physical data
Formula	C9H10FNO4
Molar mass	215.18 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1=C(C(=CC(=C1O)O)F)C[C@@H](C(=O)O)N;
	InChI InChI=1S/C9H10FNO4/c10-5-3-8(13)7(12)2-4(5)1-6(11)9(14)15/h2-3,6,12-13H,1,11H2,(H,14,15)/t6-/m0/s1; Key:PAXWQORCRCBOCU-LURJTMIESA-N;

Fluorodopa, also known as FDOPA, is a fluorinated form of L-DOPA primarily synthesized as its fluorine-18 isotopologue for use as a radiotracer in positron emission tomography.^[1] FD PET is a valid method for assessing the functional state of the nigrostriatal dopaminergic pathway. It is particularly useful for studies requiring repeated measures such as examinations of the course of a disease and the effect of treatment

References

^ Deng W-P, Wong KA, Kirk KL (2002). "Convenient syntheses of 2-, 5- and 6-fluoro- and 2,6-difluoro-L-DOPA". Tetrahedron: Asymmetry. 13 (11): 1135–1140. doi:10.1016/S0957-4166(02)00321-X. {{cite journal}}: Cite has empty unknown parameter: |month= (help)CS1 maint: multiple names: authors list (link)

[Deng_2002-1] Deng W-P, Wong KA, Kirk KL (2002). "Convenient syntheses of 2-, 5- and 6-fluoro- and 2,6-difluoro-L-DOPA". Tetrahedron: Asymmetry. 13 (11): 1135–1140. doi:10.1016/S0957-4166(02)00321-X. {{cite journal}}: Cite has empty unknown parameter: |month= (help)CS1 maint: multiple names: authors list (link)

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