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Fusicocca-2,10(14)-diene synthase

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Fusicocca-2,10(14)-diene synthase
Identifiers
EC no.4.2.3.43
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins

Fusicocca-2,10(14)-diene synthase (EC 4.2.3.43, fusicoccadiene synthase, PaFS, PaDC4) is an enzyme with systematic name geranylgeranyl diphosphate-lyase (fusicocca-2,10(14)-diene-forming).[1] This enzyme catalyses the following chemical reaction

geranylgeranyl diphosphate fusicocca-2,10(14)-diene + diphosphate

This multifunctional enzyme also has EC 2.5.1.29, farnesyltranstransferase, activity.

References

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  1. ^ Toyomasu T, Tsukahara M, Kaneko A, Niida R, Mitsuhashi W, Dairi T, Kato N, Sassa T (February 2007). "Fusicoccins are biosynthesized by an unusual chimera diterpene synthase in fungi". Proceedings of the National Academy of Sciences of the United States of America. 104 (9): 3084–8. doi:10.1073/pnas.0608426104. PMC 1805559. PMID 17360612.
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