GAL3ST4

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GAL3ST4
Identifiers
Aliases GAL3ST4, GAL3ST-4, galactose-3-O-sulfotransferase 4
External IDs MGI: 1916254 HomoloGene: 11633 GeneCards: GAL3ST4
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_024637

NM_001033416
NM_001347507

RefSeq (protein)

NP_078913

n/a

Location (UCSC) Chr 7: 100.16 – 100.17 Mb Chr 5: 138.26 – 138.27 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Galactose-3-O-sulfotransferase 4 is an enzyme that in humans is encoded by the GAL3ST4 gene.[3][4]

This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate to the C-3' position of galactose residues in O-linked glycoproteins. This enzyme is highly specific for core 1 structures, with asialofetuin, Gal-beta-1,3-GalNAc and Gal-beta-1,3 (GlcNAc-beta-1,6)GalNAc being good substrates.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Seko A, Hara-Kuge S, Yamashita K (Jul 2001). "Molecular cloning and characterization of a novel human galactose 3-O-sulfotransferase that transfers sulfate to gal beta 1-->3galNAc residue in O-glycans". J Biol Chem. 276 (28): 25697–704. doi:10.1074/jbc.M101558200. PMID 11333265. 
  4. ^ a b "Entrez Gene: GAL3ST4 galactose-3-O-sulfotransferase 4". 

Further reading[edit]