GAS2L1

GAS2L1
Identifiers
Aliases	GAS2L1, GAR22, growth arrest specific 2 like 1
External IDs	OMIM: 602128; MGI: 1926176; HomoloGene: 4733; GeneCards: GAS2L1; OMA:GAS2L1 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	29,312,785 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	5,015,327 bp
RNA expression pattern
	Top expressed in
	gingival epithelium; ; tendon of biceps brachii; ; seminal vesicula; ; endothelial cell; ; Region I of hippocampus proper; ; dorsal motor nucleus of vagus nerve; ; olfactory bulb; ; Brodmann area 23; ; primary visual cortex; ; parotid gland;
	Top expressed in
	otic vesicle; ; blood; ; lip; ; seminiferous tubule; ; internal carotid artery; ; olfactory epithelium; ; skin of external ear; ; external carotid artery; ; endothelial cell of lymphatic vessel; ; stroma of bone marrow;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	cytoskeletal anchor activity; thyroid hormone receptor binding; microtubule binding;
Cellular component	cytoplasm; microtubule; cytoskeleton; stress fiber;
Biological process	cellular response to starvation; negative regulation of microtubule depolymerization; negative regulation of cell growth; microtubule bundle formation; negative regulation of gene expression; negative regulation of erythrocyte differentiation; cellular response to thyroid hormone stimulus; regulation of cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	10634
	78926
	ENSG00000185340
	ENSMUSG00000034201
	Q99501
	Q8JZP9
NM_001278730; NM_006478; NM_152236; NM_152237; NM_001362985;
	NM_001395196; NM_001395197
	NM_001190406; NM_001190408; NM_030228; NM_144560
	NP_001265659; NP_006469; NP_689422; NP_689423; NP_001349914
	NP_001177335; NP_001177337; NP_084504; NP_653146
	Wikidata
View/Edit Human	View/Edit Mouse

GAS2-like protein 1 is a protein that in humans is encoded by the GAS2L1 gene.^[5]^[6]^[7]^[8]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000185340 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000034201 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Zucman-Rossi J, Legoix P, Thomas G (Mar 1997). "Identification of new members of the Gas2 and Ras families in the 22q12 chromosome region". Genomics. 38 (3): 247–54. doi:10.1006/geno.1996.0625. PMID 8975699.
^ Goriounov D, Leung CL, Liem RK (Feb 2003). "Protein products of human Gas2-related genes on chromosomes 17 and 22 (hGAR17 and hGAR22) associate with both microfilaments and microtubules". J Cell Sci. 116 (Pt 6): 1045–58. doi:10.1242/jcs.00272. PMID 12584248.
^ Brancolini C, Bottega S, Schneider C (Jul 1992). "Gas2, a growth arrest-specific protein, is a component of the microfilament network system". J Cell Biol. 117 (6): 1251–61. doi:10.1083/jcb.117.6.1251. PMC 2289493. PMID 1607387.
^ "Entrez Gene: GAS2L1 growth arrest-specific 2 like 1".

References

Further reading