GSDMD
Gasdermin D is a protein that in humans is encoded by the GSDMD gene. [5]
Function
Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.
References
- ^ a b c ENSG00000104518 GRCh38: Ensembl release 89: ENSG00000278718, ENSG00000104518 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022575 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Gasdermin D". Retrieved 2016-08-26.
Further reading
- Saeki N, Usui T, Aoyagi K, Kim DH, Sato M, Mabuchi T, Yanagihara K, Ogawa K, Sakamoto H, Yoshida T, Sasaki H (2009). "Distinctive expression and function of four GSDM family genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium". Genes Chromosomes Cancer. 48 (3): 261–71. doi:10.1002/gcc.20636. PMID 19051310.
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.