Gamma-muurolene synthase
| Gamma-muurolene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.126 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Gamma-muurolene synthase (EC 4.2.3.126, Cop3) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lase (cyclizing, gamma-muurolene-forming).[1][2] This enzyme catalyses the following chemical reaction
- (2E,6E)-farnesyl diphosphate gamma-muurolene + diphosphate
The enzyme has been characterized from the fungus Coprinus cinereus.
References
- ^ Agger, S.; Lopez-Gallego, F.; Schmidt-Dannert, C. (2009). "Diversity of sesquiterpene synthases in the basidiomycete Coprinus cinereus". Mol. Microbiol. 72: 1181–1195. doi:10.1111/j.1365-2958.2009.06717.x. PMC 2723806. PMID 19400802.
- ^ Lopez-Gallego, F.; Wawrzyn, G.T.; Schmidt-Dannert, C. (2010). "Selectivity of fungal sesquiterpene synthases: role of the active site’s H-1α loop in catalysis". Appl. Environ. Microbiol. 76: 7723–7733. doi:10.1128/aem.01811-10. PMC 2988597. PMID 20889795.
External links
- Gamma-muurolene+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)