Jump to content

Growth hormone secretagogue

Add links
From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by Vanished user 0x8cSXE0x6 (talk | contribs) at 01:24, 23 June 2015. The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Growth hormone secretagogues (GSHs) are a class of drugs which act as secretagogues (i.e., induce the secretion) of growth hormone (GH). They include agonists of the ghrelin/growth hormone secretagogue receptor (GHSR), such as ghrelin (lenomorelin), pralmorelin (GHRP-2), GHRP-6, examorelin (hexarelin), ipamorelin, and ibutamoren (MK-677), and agonists of the growth hormone-releasing hormone receptor (GHRHR), such as growth hormone-releasing hormone (GHRH) (somatorelin), CJC-1295, sermorelin, and tesamorelin. Many also induce the secretion of insulin-like growth factor 1 (IGF-1), as well as of other hypothalamic-pituitary hormones such as prolactin and cortisol. The main clinical application of these agents is the treatment of growth hormone deficiency. They also see black market use, similarly to anabolic steroids, for bodybuilding purposes.

References


Template:Neuropeptidergics Template:Peptidergics


Stub icon

This pharmacology-related article is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=Growth_hormone_secretagogue&oldid=668221387"