HECTD4

HECTD4
Identifiers
Aliases	HECTD4, C12orf51, POTAGE, HECT domain E3 ubiquitin protein ligase 4, HEEL, C12ord51
External IDs	MGI: 3647820; HomoloGene: 28297; GeneCards: HECTD4; OMA:HECTD4 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	112,382,439 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	121,506,640 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; middle temporal gyrus; ; ganglionic eminence; ; Brodmann area 23; ; paraflocculus of cerebellum; ; cerebellar vermis; ; right frontal lobe; ; primary visual cortex; ; Brodmann area 9; ; prefrontal cortex;
	Top expressed in
	superior cervical ganglion; ; medial dorsal nucleus; ; visual cortex; ; subiculum; ; piriform cortex; ; central gray substance of midbrain; ; medial geniculate nucleus; ; primary visual cortex; ; superior colliculus; ; inferior colliculi;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; ubiquitin-protein transferase activity; ubiquitin protein ligase activity;
Cellular component	integral component of membrane; membrane; cytoplasm;
Biological process	protein ubiquitination; glucose homeostasis; glucose metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	283450
	269700
	ENSG00000173064
	ENSMUSG00000042744
	Q9Y4D8
	n/a
	NM_173813; NM_001109662; NM_001388303
	NM_181421
	NP_001103132
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

HECT domain E3 ubiquitin protein ligase 4 is a protein that in humans is encoded by the HECTD4 gene. ^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000173064 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000042744 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: HECT domain E3 ubiquitin protein ligase 4". Retrieved 2016-10-24.

Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
Go MJ, Hwang JY, Kim YJ, Hee Oh J, Kim YJ, Heon Kwak S, Soo Park K, Lee J, Kim BJ, Han BG, Cho MC, Cho YS, Lee JY (2013). "New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population". J. Hum. Genet. 58 (6): 362–5. doi:10.1038/jhg.2013.14. PMID 23575436.

This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it.