HIST1H3C

HIST1H3C
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3WKJ, 3B95, 2C1J, 3AYW, 3WA9, 3U4S, 5AVB, 2CV5, 5AV5, 3U31, 2UXN, 3AZK, 2C1N, 5C11, 3QO2, 3X1V, 5C13, 4A0J, 4U68, 5AV8, 4LLB, 3U5O, 1O9S, 4FT2, 4HON, 3W99, 3ZVY, 4Z0R, 5AVC, 1CT6, 1Q3L, 3O37, 3W97, 3SOW, 3KMT, 4YM6, 4A7J, 3UEE, 2KWK, 4F4U, 3UEF, 3UIG, 4BD3, 3AZL, 4QBR, 4F56, 3AFA, 4LKA, 5CPK, 5FFV, 3V43, 5CH1, 3U5P, 3AZI, 3U5N, 3AZH, 3UIK, 4QBQ, 1U35, 4UY4, 2OT7, 5AV9, 2B2W, 3U3D, 3AZF, 3W98, 4I51, 4X3K, 4FWF, 2B2T, 2B2V, 4A0N, 2KWJ, 3WAA, 3QJ6, 5DAH, 3AZG, 3AZE, 3X1T, 3RIY, 2L75, 3A1B, 2VPG, 4QBS, 3O35, 5CPJ, 3ZG6, 4YM5, 3AZJ, 2RI7, 3AZN, 3AVR, 5CPI, 2LBM, 3W96, 3O34, 2M0O, 4L7X, 5CH2, 5AV6, 3AZM, 4UP0, 3X1S, 2OX0, 3UII, 3SOU, 4N4H, 4TN7, 1CS9, 3X1U, 4LXL, 2B2U, 2OQ6, 3RIG, 5C3I, 4YHP, 5B24, 5D6Y, 4YHZ, 4Z2M, 5HJD, 5HJC, 5HJB, 5B2I, 5HYN, 5FB0, 5FB1, 5IQL, 5B2J, 5JIN
Identifiers
Aliases	HIST1H3C, H3.1, H3/c, H3FC, histone cluster 1, H3c, histone cluster 1 H3 family member c, H3C3
External IDs	OMIM: 602812; MGI: 2448355; HomoloGene: 134495; GeneCards: HIST1H3C; OMA:HIST1H3C - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	26,045,821 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	96,155,825 bp
RNA expression pattern
	Top expressed in
	stomach; ; colon; ; lung; ; kidney; ; heart; ; vagina; ; ovary; ; testicle;
	Top expressed in
	genital tubercle; ; secondary oocyte; ; primary oocyte; ; embryo; ; zygote; ; embryo; ; morula; ; tail of embryo; ; bone marrow; ; epiblast;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; histone binding; protein binding; protein heterodimerization activity; cadherin binding; nucleosomal DNA binding;
Cellular component	membrane; nucleoplasm; chromosome; extracellular region; nuclear chromosome; extracellular exosome; nucleosome; nucleus; protein-containing complex;
Biological process	telomere organization; epigenetic maintenance of chromatin in transcription-competent conformation; protein heterotetramerization; blood coagulation; DNA replication-dependent chromatin assembly; rDNA heterochromatin assembly; negative regulation of gene expression, epigenetic; chromatin organization; regulation of gene silencing by miRNA; nucleosome assembly; interleukin-7-mediated signaling pathway; regulation of megakaryocyte differentiation; regulation of hematopoietic stem cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	8352
	15077
	ENSG00000278272
	ENSMUSG00000093769
	P68431
	P84228
	NM_003531
	NM_178216
	NP_066298; NP_003520; NP_003525; NP_003527
NP_473386; NP_835734; NP_783584; NP_835510; NP_835587;
	NP_038576; NP_835511; NP_835512
	Wikidata
View/Edit Human	View/Edit Mouse

Histone H3.1 is a protein that in humans is encoded by the HIST1H3C gene.^[5]^[6]^[7]^[8]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000278272 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000093769 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kardalinou E, Eick S, Albig W, Doenecke D (Dec 1993). "Association of a human H1 histone gene with an H2A pseudogene and genes encoding H2B.1 and H3.1 histones". J Cell Biochem. 52 (4): 375–83. doi:10.1002/jcb.240520402. PMID 8227173.
^ Albig W, Kioschis P, Poustka A, Meergans K, Doenecke D (Apr 1997). "Human histone gene organization: nonregular arrangement within a large cluster". Genomics. 40 (2): 314–22. doi:10.1006/geno.1996.4592. PMID 9119399.
^ Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ (Oct 2002). "The human and mouse replication-dependent histone genes". Genomics. 80 (5): 487–98. doi:10.1016/S0888-7543(02)96850-3. PMID 12408966.
^ "Entrez Gene: HIST1H3C histone cluster 1, H3c".

References

Further reading