HIST1H4K

H4C12
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4H9O, 3WKJ, 3AYW, 3WA9, 5B0Z, 5AVB, 2CV5, 5AV5, 3AV2, 3WTP, 3AV1, 3AZK, 3X1V, 5AV8, 1F66, 4QUU, 3CFS, 4YYK, 4QUT, 3NQJ, 3A6N, 3W99, 5AVC, 2RS9, 3F9Z, 3QZT, 3QBY, 3W97, 4M38, 4YM6, 3CFV, 4HGA, 1EQZ, 2RJE, 3QZV, 1HQ3, 4H9P, 3AZL, 3AFA, 1TZY, 3UVY, 5CPK, 3JPX, 4U9W, 4N3W, 4YYJ, 4YYD, 4H9N, 4H9R, 3AZI, 4LD9, 3UVX, 3AZH, 5BNX, 4N4F, 1U35, 4YYG, 3O36, 2ARO, 5AV9, 4H9S, 3AZF, 3W98, 4GQB, 4H9Q, 5BNV, 3WAA, 3AZG, 3AZE, 2RNY, 1ZKK, 2QQS, 2LVM, 3X1T, 3AN2, 2KWO, 3QZS, 3F9W, 5FFW, 5CPJ, 3F9X, 3IJ1, 4YM5, 3AZJ, 4YY6, 3AZN, 2IG0, 4YYH, 4YYI, 5CPI, 3W96, 3R45, 2KWN, 3F9Y, 5AV6, 3AZM, 5BO0, 3X1S, 4QYD, 4KGC, 3UVW, 4YYN, 3X1U, 3UW9, 2F8N, 3NQU, 5B0Y, 4YYM, 5C3I, 4Z5T, 5B24, 5FA5, 4Z2M, 5E5A, 5FWE, 5B2I, 5B40, 5B2J, 5JA4, 5AY8, 4ZUX
Identifiers
Aliases	H4C12, H4/d, H4F2iii, H4FD, dJ160A22.1, histone cluster 1, H4k, histone cluster 1 H4 family member k, HIST1H4K, H4 clustered histone 12, H4C5, H4C4, H4C9, H4-16, H4C3, H4C13, H4C11, H4C1, H4C14, H4C15, H4C8, H4C6, H4C2
External IDs	OMIM: 602825; MGI: 2448436; HomoloGene: 134474; GeneCards: H4C12; OMA:H4C12 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	27,831,560 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	21,920,007 bp
RNA expression pattern
	Top expressed in
	bone marrow cells; ; corpus callosum; ; testicle; ; mucosa of transverse colon; ; epithelium of colon; ; right lobe of liver; ; monocyte; ; granulocyte; ; tonsil; ; blood;
	Top expressed in
	islet of Langerhans; ; embryo; ; embryo; ; spermatid; ; renal corpuscle; ; genital tubercle; ; yolk sac; ; medullary collecting duct; ; spermatocyte; ; vestibular membrane of cochlear duct;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein domain specific binding; protein binding; protein heterodimerization activity; DNA binding; histone binding; RNA binding;
Cellular component	membrane; chromosome; nucleoplasm; extracellular region; nuclear chromosome; nucleosome; extracellular exosome; nucleus; extracellular matrix; protein-containing complex;
Biological process	telomere organization; epigenetic maintenance of chromatin in transcription-competent conformation; protein heterotetramerization; negative regulation of megakaryocyte differentiation; CENP-A containing chromatin assembly; DNA replication-dependent chromatin assembly; rDNA heterochromatin assembly; negative regulation of gene expression, epigenetic; DNA-templated transcription, initiation; double-strand break repair via nonhomologous end joining; beta-catenin-TCF complex assembly; telomere capping; nucleosome assembly; regulation of gene silencing by miRNA; regulation of megakaryocyte differentiation; regulation of hematopoietic stem cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	8362
	319159
	ENSG00000273542
	ENSMUSG00000067455
	P62805
	P62806
	NM_003541
	NM_178210
NP_003537; NP_003486; NP_003535; NP_003539; NP_003531;
	NP_003536
NP_291074; NP_783587; NP_783588; NP_835499; NP_835500;
	NP_001182350; NP_835515; NP_783585; NP_783586; NP_835582; NP_835583; NP_783583; NP_694813
	Wikidata
View/Edit Human	View/Edit Mouse

Histone H4 is a protein that in humans is encoded by the HIST1H4K gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000273542 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000067455 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Albig W, Doenecke D (Feb 1998). "The human histone gene cluster at the D6S105 locus". Hum Genet. 101 (3): 284–94. doi:10.1007/s004390050630. PMID 9439656.
^ Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ (Oct 2002). "The human and mouse replication-dependent histone genes". Genomics. 80 (5): 487–98. doi:10.1016/S0888-7543(02)96850-3. PMID 12408966.
^ "Entrez Gene: HIST1H4K histone cluster 1, H4k".

References

Further reading