Hemicentin 1

HMCN1
Identifiers
Aliases	HMCN1, ARMD1, FBLN6, FIBL-6, FIBL6, hemicentin 1
External IDs	OMIM: 608548; MGI: 2685047; HomoloGene: 23741; GeneCards: HMCN1; OMA:HMCN1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	186,190,949 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	150,869,186 bp
RNA expression pattern
	Top expressed in
	Descending thoracic aorta; ; ascending aorta; ; visceral pleura; ; right coronary artery; ; skin of hip; ; left coronary artery; ; synovial membrane; ; synovial joint; ; cardiac muscle tissue of right atrium; ; right lung;
	Top expressed in
	hand; ; atrium; ; Gonadal ridge; ; atrioventricular valve; ; external carotid artery; ; vas deferens; ; dermis; ; vestibular membrane of cochlear duct; ; condyle; ; lung;
	More reference expression data
	n/a
Gene ontology
Molecular function	calcium ion binding; extracellular matrix structural constituent; signaling receptor activity; protein homodimerization activity; cell adhesion molecule binding;
Cellular component	extracellular matrix; extracellular region; basement membrane; cell junction; cell cortex; extracellular exosome; cytoplasm; cleavage furrow; collagen-containing extracellular matrix;
Biological process	response to stimulus; visual perception; cell cycle; cell division; homophilic cell adhesion via plasma membrane adhesion molecules; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; response to bacterium;
	Sources:Amigo / QuickGO
Orthologs
	83872
	545370
	ENSG00000143341
	ENSMUSG00000066842
	Q96RW7
	D3YXG0
	NM_031935
	NM_001024720
	NP_114141
	NP_001019891
	Wikidata
View/Edit Human	View/Edit Mouse

Hemicentin-1 is a protein that in humans is encoded by the HMCN1 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000143341 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000066842 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Vogel BE, Hedgecock EM (Mar 2001). "Hemicentin, a conserved extracellular member of the immunoglobulin superfamily, organizes epithelial and other cell attachments into oriented line-shaped junctions". Development. 128 (6): 883–94. PMID 11222143.
^ "Entrez Gene: HMCN1 hemicentin 1".

References

Further reading