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|Artery||Greater palatine artery|
|Nerve||Greater palatine nerve, nasopalatine nerve|
The hard palate is a thin horizontal bony plate made up of two bones of the facial skeleton, located in the roof of the mouth. The bones are the palatine process of the maxilla and the horizontal plate of palatine bone. The hard palate spans the alveolar arch formed by the alveolar process that holds the upper teeth (when these are developed).
The hard palate is formed by the palatine process of the maxilla and horizontal plate of palatine bone. It forms a partition between the nasal passages and the mouth. On the anterior portion of the hard palate are the plicae, irregular ridges in the mucous membrane that help facilitate the movement of food backward towards the larynx. This partition is continued deeper into the mouth by a fleshy extension called the soft palate.
On the ventral surface of hard palate, some projections or transverse ridges are present which are called as palatine rugae.
The hard palate is important for feeding and speech. Mammals with a defective hard palate may die shortly after birth due to inability to suckle. It is also involved in mastication in many species. The interaction between the tongue and the hard palate is essential in the formation of certain speech sounds, notably high-front vowels, palatal consonants, and retroflex consonants such as [i] like "see", [j] like "yes", [ç] (realization of /hj/ in English) like "hue", and [ɻ] (/r/, only for some speakers) like "red".
In the birth defect called cleft palate, the left and right portions of this plate are not joined, forming a gap between the mouth and nasal passage (a related defect affecting the face is cleft lip).
While a cleft palate has a severe impact upon the ability to nurse and speak, it is now successfully treated through reconstructive surgical procedures at an early age. This is the time where such procedures are available.
Due to the complexity of this birth defect, researchers still do not know exactly what causes the cleft palate to develop during human development. Recently, these researchers found that even though there is no exact cause, there are several risk factors that drastically increase the risk of a baby being born with an orofacial cleft palate. As for the environmental risk factors, maternal smoking is the most influential risk factor. Based on a recent study of 103 German patients with cleft palates, it was found that 25.2% of them developed the defect due to excessive maternal smoking during pregnancy.
While maternal smoking during pregnancy is a risk, there are also several genetic risk factors. Five SNP variants in the PAX7 gene affect development of facial features. These variations occur at six loci: 1p36, 2p21, 3p11.1, 8q21.3, 13q31.1 and 15q22. When tested in the European and Asian communities, these loci tests had a 95% acceptance rate. Besides the PAX 7 gene variants, there were also five possible mutations found in the transforming growth factor- alpha gene or TGFA gene that can lead to the development of a cleft palate. Even though several risk factors have been linked to cleft palates, more research much be done in order to determine the true causes of the defect.
Hard palate pigmentation
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