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Hendrik Dietz

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Hendrik Dietz
Born(1977-12-18)18 December 1977
Dresden, Germany
NationalityGerman
Alma materTechnical University Munich
Ludwig Maximilian University of Munich
Paderborn University
Known forDNA Origami
AwardsLeibniz Prize (2015)
Scientific career
FieldsPhysics
InstitutionsTechnical University Munich
Harvard University

Hendrik Dietz (born December 18, 1977, in Dresden Germany) is a German physicist known for his contributions in the field of DNA origami. He is a full-professor for biophysics at the Technical University of Munich.

Life

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Dietz studied physics in Paderborn University, the University of Zaragoza, and at the LMU Munich. He completed his studies with a diploma in 2004. Subsequently, he became a research associate at the Technical University of Munich (TUM). In 2007, he earned his Dr. rer. nat. with research on the mechanical anisotropy of proteins in single-molecule experiments.[1] After that, he spent two years as a postdoc at Harvard University. Since the summer of 2009, he has been a Professor of Biophysics at the TU München.

Research

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Dietz’s main research focus is on DNA nanotechnology. He uses DNA origami to design molecular machines that can execute user-defined tasks. Among these devices are force-sensing nano-structures,[2] gigadalton-sized DNA assemblies,[3] dynamically switching devices,[4] molecular motors,[5][6] and virus traps.[7][8]

In the long term, Dietz hopes to make a significant contribution to the creation of molecular machines and systems with practical benefits for everyday life. This includes uses in medicine such as vaccines or drug delivery vehicles and synthetic enzymes for biologically inspired chemistry.[citation needed]

Awards

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References

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  1. ^ Dietz, Hendrik (2007). Mechanische Anisotropie von Proteinen in Einzelmolekülexperimenten (Thesis). Technische Universität München.
  2. ^ Funke, Jonas J.; Ketterer, Philip; Lieleg, Corinna; Schunter, Sarah; Korber, Philipp; Dietz, Hendrik (2016-11-04). "Uncovering the forces between nucleosomes using DNA origami". Science Advances. 2 (11): e1600974. Bibcode:2016SciA....2E0974F. doi:10.1126/sciadv.1600974. ISSN 2375-2548. PMC 5262459. PMID 28138524.
  3. ^ Wagenbauer, Klaus F.; Sigl, Christian; Dietz, Hendrik (2017-12-07). "Gigadalton-scale shape-programmable DNA assemblies". Nature. 552 (7683): 78–83. Bibcode:2017Natur.552...78W. doi:10.1038/nature24651. ISSN 1476-4687. PMID 29219966. S2CID 205262182.
  4. ^ Gerling, Thomas; Wagenbauer, Klaus F.; Neuner, Andrea M.; Dietz, Hendrik (2015-03-27). "Dynamic DNA devices and assemblies formed by shape-complementary, non–base pairing 3D components". Science. 347 (6229): 1446–1452. Bibcode:2015Sci...347.1446G. doi:10.1126/science.aaa5372. ISSN 0036-8075. PMID 25814577. S2CID 22642035.
  5. ^ Pumm, Anna-Katharina; Engelen, Wouter; Kopperger, Enzo; Isensee, Jonas; Vogt, Matthias; Kozina, Viktorija; Kube, Massimo; Honemann, Maximilian N.; Bertosin, Eva; Langecker, Martin; Golestanian, Ramin; Simmel, Friedrich C.; Dietz, Hendrik (2022-07-20). "A DNA origami rotary ratchet motor". Nature. 607 (7919): 492–498. Bibcode:2022Natur.607..492P. doi:10.1038/s41586-022-04910-y. ISSN 1476-4687. PMC 9300469. PMID 35859200.
  6. ^ Shi, Xin; Pumm, Anna-Katharina; Isensee, Jonas; Zhao, Wenxuan; Verschueren, Daniel; Martin-Gonzalez, Alejandro; Golestanian, Ramin; Dietz, Hendrik; Dekker, Cees (2022-08-04). "Sustained unidirectional rotation of a self-organized DNA rotor on a nanopore". Nature Physics. 18 (9): 1105–1111. arXiv:2206.06613. Bibcode:2022NatPh..18.1105S. doi:10.1038/s41567-022-01683-z. ISSN 1745-2481. S2CID 256747052.
  7. ^ Sigl, Christian; Willner, Elena M.; Engelen, Wouter; Kretzmann, Jessica A.; Sachenbacher, Ken; Liedl, Anna; Kolbe, Fenna; Wilsch, Florian; Aghvami, S. Ali; Protzer, Ulrike; Hagan, Michael F.; Fraden, Seth; Dietz, Hendrik (2021-06-14). "Programmable icosahedral shell system for virus trapping". Nature Materials. 20 (9): 1281–1289. Bibcode:2021NatMa..20.1281S. doi:10.1038/s41563-021-01020-4. ISSN 1476-4660. PMC 7611604. PMID 34127822.
  8. ^ Monferrer, Alba; Kretzmann, Jessica A.; Sigl, Christian; Sapelza, Pia; Liedl, Anna; Wittmann, Barbara; Dietz, Hendrik (2022-12-27). "Broad-Spectrum Virus Trapping with Heparan Sulfate-Modified DNA Origami Shells". ACS Nano. 16 (12): 20002–20009. doi:10.1021/acsnano.1c11328. ISSN 1936-0851. PMC 9798855. PMID 36323320.
  9. ^ "Biography Hendrik Dietz". Dietz Lab for Biomolecular Design (in German). Retrieved 2023-08-21.
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