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Humanes is a municipality of Spain in the province of Guadalajara, an autonomous community of Castilla-La Mancha, with an area of 48.98 km² (18.91 mi²), population of 1,272 (2004 estimate), and a density of 26.51 people/km² (67.27 people/mi²).

Coordinates: 40°49′38″N 3°09′19″W / 40.82722°N 3.15528°W / 40.82722; -3.15528