Hydroxymethylbilane

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Hydroxymethylbilane
Hydroxymethylbilane.svg
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
MeSH hydroxymethylbilane
Properties
C40H46N4O17
Molar mass 854.81 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Hydroxymethylbilane (HMB), also known as preuroporphyrinogen, is a molecule involved in the metabolism of porphyrin. In the third step, it is generated by the enzyme porphobilinogen deaminase, and in the next step the enzyme uroporphyrinogen III synthase converts it into uroporphyrinogen III.

In general, defects of heme synthesis after formation of HMB lead to photosensitivity.