INPP4A

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
INPP4A
Identifiers
AliasesINPP4A, INPP4, TVAS1, inositol polyphosphate-4-phosphatase type I A
External IDsMGI: 1931123 HomoloGene: 2871 GeneCards: INPP4A
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for INPP4A
Genomic location for INPP4A
Band2q11.2Start98,444,854 bp[1]
End98,594,390 bp[1]
RNA expression pattern
PBB GE INPP4A 208363 s at fs.png

PBB GE INPP4A 208364 at fs.png

PBB GE INPP4A 204553 x at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001290797
NM_001290798
NM_001290799
NM_030266
NM_172971

RefSeq (protein)

NP_001277726
NP_001277727
NP_001277728
NP_084542
NP_766559

Location (UCSC)Chr 2: 98.44 – 98.59 MbChr 1: 37.3 – 37.41 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Type I inositol-3,4-bisphosphate 4-phosphatase is an enzyme that in humans is encoded by the INPP4A gene.[5][6][7]

INPP4A encodes the inositol polyphosphate 4-phosphatase type I, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate.[7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000040933 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026113 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Norris FA, Auethavekiat V, Majerus PW (Aug 1995). "The isolation and characterization of cDNA encoding human and rat brain inositol polyphosphate 4-phosphatase". J Biol Chem. 270 (27): 16128–33. doi:10.1074/jbc.270.27.16128. PMID 7608176.
  6. ^ Norris FA, Atkins RC, Majerus PW (Oct 1997). "The cDNA cloning and characterization of inositol polyphosphate 4-phosphatase type II. Evidence for conserved alternative splicing in the 4-phosphatase family". J Biol Chem. 272 (38): 23859–64. doi:10.1074/jbc.272.38.23859. PMID 9295334.
  7. ^ a b "Entrez Gene: INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa".

Further reading[edit]