IPO13

IPO13
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2X19, 2XWU, 3ZJY
Identifiers
Aliases	IPO13, IMP13, KAP13, LGL2, RANBP13, importin 13
External IDs	OMIM: 610411; MGI: 2385205; HomoloGene: 40968; GeneCards: IPO13; OMA:IPO13 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	43,968,022 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	117,772,196 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; putamen; ; corpus callosum; ; inferior ganglion of vagus nerve; ; external globus pallidus; ; olfactory bulb; ; caudate nucleus; ; amygdala; ; nucleus accumbens; ; subthalamic nucleus;
	Top expressed in
	skeletal muscle tissue; ; knee joint; ; vastus lateralis muscle; ; extraocular muscle; ; temporal muscle; ; triceps brachii muscle; ; ankle; ; digastric muscle; ; tibialis anterior muscle; ; thoracic diaphragm;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; nuclear localization sequence binding;
Cellular component	nucleus; nuclear membrane; cytoplasm;
Biological process	protein import into nucleus; protein transport; intracellular protein transport;
	Sources:Amigo / QuickGO
Orthologs
	9670
	230673
	ENSG00000117408
	ENSMUSG00000033365
	O94829
	Q8K0C1
	NM_014652
	NM_146152
	NP_055467
	NP_666264
	Wikidata
View/Edit Human	View/Edit Mouse

Importin-13 is a protein that in humans is encoded by the IPO13 gene.^[5]^[6]^[7]

Interactions

IPO13 has been shown to interact with RBM8A,^[6] PAX6,^[8]^[9] ALX1,^[9] EIF1AX^[6] and UBE2I.^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000117408 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000033365 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Oct 1998). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.
^ ^a ^b ^c ^d Mingot JM, Kostka S, Kraft R, Hartmann E, Görlich D (Jul 2001). "Importin 13: a novel mediator of nuclear import and export". The EMBO Journal. 20 (14): 3685–94. doi:10.1093/emboj/20.14.3685. PMC 125545. PMID 11447110.
^ "Entrez Gene: IPO13 importin 13".
^ Ploski JE, Shamsher MK, Radu A (Jun 2004). "Paired-type homeodomain transcription factors are imported into the nucleus by karyopherin 13". Molecular and Cellular Biology. 24 (11): 4824–34. doi:10.1128/MCB.24.11.4824-4834.2004. PMC 416398. PMID 15143176.
^ ^a ^b Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, et al. (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.

Interactions

References

Further reading