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James Wilson (scientist)

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James M. Wilson is an American geneticist and medical researcher, known for his work on gene therapy, where he was regarded as one of the field's most prominent researchers[1] until ethical concerns arose around the death of of a patient in one of his trials.[1][2]

Biography

Wilson gained his BA in chemistry at Albion College in 1977, and his MD and PhD at the University of Michigan in 1984.[3] As of 2016, he works at the Penn Cardiovascular Institute of the University of Pennsylvania.[3][4] His research interests include genetic disorders of lipid metabolism, and gene therapy for dyslipidemias, coronary artery disease and congestive heart failure.[3]

In 1999, a patient in a clinical trial led by Wilson, Jesse Gelsinger, died after receiving a gene therapy treatment. Further investigation showed improper consent forms and that Wilson had significant financial stakes in the success of the trial.[1][2]

References

  1. ^ a b c Gene Therapy Emerges From Disgrace to Be the Next Big Thing, Again by Carl Zimmer August 13, 2013 Wired
  2. ^ a b James M. Wilson (2009), "A History Lesson for Stem Cells", Science, 324: 727–728, doi:10.1126/science.1174935, JSTOR 20493877 {{citation}}: Unknown parameter |registration= ignored (|url-access= suggested) (help)
  3. ^ a b c James M. Wilson, University of Pennsylvania
  4. ^ Gene therapy; an interview Scientific American