Jerome Vinograd

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Jerome Vinograd
Born(1913-02-09)February 9, 1913
DiedJuly 7, 1976(1976-07-07) (aged 63)
Alma materUniversity of Minnesota
University of California, Los Angeles
Known forDensity gradient ultracentrifugation
DNA supercoiling
AwardsKendall Award
Scientific career
InstitutionsCalifornia Institute of Technology
Doctoral advisorJames William McBain
A scanned image of Jerome Vinograd's signature.

Jerome Vinograd (February 9, 1913 – July 7, 1976) was an American biochemist who developed density gradient ultracentrifugation and contributed to the understanding of DNA supercoiling.[1][2]


Vinograd obtained his undergraduate degree in chemistry from the University of Minnesota. From 1931 to 1933 he studied colloid chemistry with Professor Herbert Freundlich at the University of Berlin, and from 1933 to 1935 continued his studies with Freundlich at University College, London. In 1936 he went to the University of California, Los Angeles and obtained in Master of Arts degree in organic chemistry with Professor William G. Young. In 1937 he married Sherna Shalett.[2] He obtained his Ph.D. in Chemistry in 1940 with Professor James W. McBain at Stanford University with research on physical and colloid chemistry.[1]


From 1941 to 1951, Vinograd worked for the Shell Development Company in Emeryville, California. During this period, his wife Sherna bore their two daughters, Julia and Deborah.[2] In 1951 he became a Senior Research Fellow at the California Institute of Technology, in Pasadena, California, where he remained for the rest of his career. In 1956 he became a Research Associate, and in 1965 he was promoted to Professor of Chemistry and Biology. He pioneered the use of ultracentrifugation for the analysis of complex molecules, in particular DNA.

Awards and Honors[edit]

In 1968, Vinograd was elected to the National Academy of Sciences. In 1970 he received the Kendall Award from the American Chemical Society. In 1972, the Helen Hay Whitney Foundation gave him the T. Duckett Jones Award. He was invited to give a number of honorary lectures, including the Burroughs Wellcome Lecture at Harvard in 1970, the Jesse W. Beams Lecture at the University of Virginia in 1972, and the Falk-Plaut Lecture at Columbia University in 1972. [2][1]


  1. ^ a b c Bauer, William R. (May 1977). "Jerome Vinograd 1913-1976". Nucleic Acids Research. 4 (5): nil9-IV. doi:10.1093/nar/4.5.1159. ISSN 0305-1048. PMC 343747. PMID 331249.
  2. ^ a b c d Sinsheim, Robert L. (2007). "Jerome Vinograd 1913–1976" (PDF). In National Academy of Sciences. Biographical Memoirs. 89. Washington, D.C.: National Academies Press. pp. 356–367. ISBN 978-0-309-11372-4. Retrieved 2013-05-27.