LCMT2

LCMT2
Identifiers
Aliases	LCMT2, PPM2, TYW4, leucine carboxyl methyltransferase 2
External IDs	OMIM: 611246; MGI: 1353659; HomoloGene: 19642; GeneCards: LCMT2; OMA:LCMT2 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	43,330,582 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	120,971,134 bp
RNA expression pattern
	Top expressed in
	hair follicle; ; germinal epithelium; ; gingival epithelium; ; kidney tubule; ; glomerulus; ; metanephric glomerulus; ; gonad; ; palpebral conjunctiva; ; epithelium of nasopharynx; ; retinal pigment epithelium;
	Top expressed in
	right kidney; ; proximal tubule; ; otic vesicle; ; right ventricle; ; medullary collecting duct; ; medial ganglionic eminence; ; islet of Langerhans; ; epithelium of stomach; ; primitive streak; ; renal corpuscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	methyltransferase activity; transferase activity; protein binding; S-adenosylmethionine-dependent methyltransferase activity; tRNA methyltransferase activity; protein C-terminal leucine carboxyl O-methyltransferase activity;
Cellular component	cytoplasm; cytosol;
Biological process	tRNA modification; methylation; tRNA methylation; wybutosine biosynthetic process; tRNA processing; C-terminal protein methylation;
	Sources:Amigo / QuickGO
Orthologs
	9836
	329504
	ENSG00000168806
	ENSMUSG00000074890
	O60294
	Q8BYR1
	NM_014793
	NM_177846
	NP_055608
	NP_808514
	Wikidata
View/Edit Human	View/Edit Mouse

Leucine carboxyl methyltransferase 2 is an enzyme that in humans is encoded by the LCMT2 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000168806 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000074890 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nagase T, Ishikawa K, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Aug 1998). "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (1): 31–9. doi:10.1093/dnares/5.1.31. PMID 9628581.
^ Noma A, Suzuki T (Dec 2006). "Ribonucleome analysis identified enzyme genes responsible for wybutosine synthesis". Nucleic Acids Symp Ser (Oxf). 50 (50): 65–6. doi:10.1093/nass/nrl032. PMID 17150819.
^ "Entrez Gene: LCMT2 leucine carboxyl methyltransferase 2".