Lipolysis-stimulated lipoprotein receptor

LSR
Identifiers
Aliases	LSR, ILDR3, LISCH7, lipolysis stimulated lipoprotein receptor
External IDs	OMIM: 616582; MGI: 1927471; HomoloGene: 9306; GeneCards: LSR; OMA:LSR - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	35,267,964 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	30,672,889 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; right lobe of liver; ; body of pancreas; ; olfactory zone of nasal mucosa; ; minor salivary glands; ; gallbladder; ; right uterine tube; ; mucosa of sigmoid colon; ; skin of abdomen; ; rectum;
	Top expressed in
	gastric mucosa; ; mucous cell of stomach; ; epithelium of stomach; ; crypt of lieberkuhn of small intestine; ; pyloric antrum; ; left lobe of liver; ; yolk sac; ; jejunum; ; duodenum; ; epiblast;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	chylomicron; integral component of membrane; extracellular exosome; membrane; low-density lipoprotein particle; very-low-density lipoprotein particle; tricellular tight junction; plasma membrane;
Biological process	regulation of lipid metabolic process; liver development; establishment of blood-brain barrier; tricellular tight junction assembly; protein localization to tricellular tight junction;
	Sources:Amigo / QuickGO
Orthologs
	51599
	54135
	ENSG00000105699
	ENSMUSG00000001247
	Q86X29
	Q99KG5
NM_001260489; NM_001260490; NM_015925; NM_205834; NM_205835;
	NM_001385215
	NM_001164184; NM_001164185; NM_017405
	NP_001247418; NP_001247419; NP_057009; NP_991403; NP_991404
	NP_001157656; NP_001157657; NP_059101
	Wikidata
View/Edit Human	View/Edit Mouse

Lipolysis-stimulated lipoprotein receptor is a protein that in humans is encoded by the LSR gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000105699 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000001247 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Yen FT, Masson M, Clossais-Besnard N, Andre P, Grosset JM, Bougueleret L, Dumas JB, Guerassimenko O, Bihain BE (Jun 1999). "Molecular cloning of a lipolysis-stimulated remnant receptor expressed in the liver". J Biol Chem. 274 (19): 13390–8. doi:10.1074/jbc.274.19.13390. PMID 10224102.
^ "Entrez Gene: LSR lipolysis stimulated lipoprotein receptor".

García JM, Peña C, García V, et al. (2008). "Prognostic value of LISCH7 mRNA in plasma and tumor of colon cancer patients". Clin. Cancer Res. 13 (21): 6351–8. doi:10.1158/1078-0432.CCR-07-0882. PMID 17975147.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
Kim JE, Tannenbaum SR, White FM (2005). "Global phosphoproteome of HT-29 human colon adenocarcinoma cells". J. Proteome Res. 4 (4): 1339–46. doi:10.1021/pr050048h. PMID 16083285.
Benzinger A, Muster N, Koch HB, et al. (2005). "Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer". Mol. Cell. Proteomics. 4 (6): 785–95. doi:10.1074/mcp.M500021-MCP200. PMID 15778465.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. Bibcode:2004CBio...14.1436J. doi:10.1016/j.cub.2004.07.051. PMID 15324660. S2CID 2371325.
Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature. 428 (6982): 529–35. Bibcode:2004Natur.428..529G. doi:10.1038/nature02399. PMID 15057824.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000105699 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000001247 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10224102-5] Yen FT, Masson M, Clossais-Besnard N, Andre P, Grosset JM, Bougueleret L, Dumas JB, Guerassimenko O, Bihain BE (Jun 1999). "Molecular cloning of a lipolysis-stimulated remnant receptor expressed in the liver". J Biol Chem. 274 (19): 13390–8. doi:10.1074/jbc.274.19.13390. PMID 10224102.

[entrez-6] "Entrez Gene: LSR lipolysis stimulated lipoprotein receptor".

[1]

[2]

[3]

[4]

[5]

[6]

References

Further reading